An attempt was made to work out the factor shares and value shares of output in livestock sector over last 19 years and to examine in the Total Factor Productivity (TFP) growth of livestock production i.e. livestock production growth over and above the input growth in Tamil Nadu using secondary data for the period from 1999-2000 to 2017-18 from various reports on state-wise estimates of value of outputs from Central Statistics Office, Government of India and Department of Economics and Statistics, Government of Tamil Nadu. The share of milk to total value of output in Tamil Nadu decreased from 68 per cent to 27 per cent from the year 1999-2000 to 2017-18, whereas product shares of meat increased from 18.45 per cent to 64.77 per cent during the same period. During the same period, the factor shares of feed (47.65 per cent to 38.06 per cent) and dry fodder (36 per cent to 20 per cent) was decreased, in contrast to the share of green fodder (10 to 19 per cent). The value of TFP was found to be increasing gradually from the year 2000-01 to 2002-03 and drastically declined during the year 2003-04 (0.95), thereafter it increased gradually from the period 2003-04 to 2016-17, with drastic dip during 2011-12 and minor dip during 2007-08, 2013-14, 2015-16 and 2017-18. From the year 1999- 2000, the cumulative TFP index increased to 6.17 during 2004-05, 12.79 during 2010-11 and 20.38 during 2017-18 with increase of one unit per annum, which indicated good sign of livestock development in Tamil Nadu. It could be concluded that the technological interventions in livestock sector (output growth over and above the input growth) in Tamil Nadu shared about 72 per cent in the growth of livestock sector for the past 19 years.

Samples of feed ingredients were collected from the truck loads that arrived at feed processing unit located in Veterinary College and Research Institute, Orathanadu, Thanjavur, Tamil Nadu, India. Physical examination of collected samples was carried out prior to their chemical evaluation. Chemical evaluation of feed samples revealed that moisture content in maize grain ranged from 8.47% to 17.25% and high moisture was observed in samples received during the monsoon season (September to December). The crude protein content of protein supplements viz., soyabean meal, coconut oil cake, coconut deoiled cake (DOC), groundnut cake, groundnut deoiled cake, delinted decorticated cotton seed cake, sunflower deoiled cake and gingelly oil cake were 45.49, 25.11, 24.47, 36.92, 43.89, 35.36, 30.21 and 29.89 per cent on dry matter basis, respectively. The crude protein (% DMB) and crude fiber (% DMB) content of deoiled rice bran, rice bran and wheat bran were 15.47 and 16.13, 7.55 and 36.26, 14.26 and 9.47, respectively. Due to the high moisture content in maize grain 8.77% of the total truck loads of this ingredient received at the processing unit were rejected. Similarly, of the total truck loads of oil cakes received at the processing unit 20.93 % of soyabean meal, 12.5% of coconut oil cake, 20 % of coconut DOC, 22.22% of cotton seed cake and 33.33% of gingelly oil cake were rejected due to the lower crude protein and higher crude fiber contents. All truck loads of rice bran (100 %) were rejected due to their lower crude protein, higher crude fiber and Acid Insoluble Ash (AIA) content. The study thus revealed that quality control measures are essential to check the entry of poor quality raw materials before processing the feed.

Aflatoxins are produced in poultry feed by two major fungal species viz., Aspergillus flavus and Aspergillus parasiticus during hot and humid seasons. To detoxify these aflatoxins, various binders are being used in the field which are mostly synthetic compounds with possible other toxicities, the harmless beneficial probiotics are being considered as binders to neutralize the effect of aflatoxins in the feed. Bacterial organisms (probiotics) like Lactobacillus rhamnosus, Lactobacillus casei, Bacillus subtilis, Enterococcus faecium and yeast (Saccharomyces cerevisiae) were selected and their cell wall structures have been retrieved and molecular docking was performed against four types of aflatoxins namely AFB1, AFB2, AFG1 and AFG2. The results revealed that cell wall components of the chosen bacterial organisms have a good binding affinity towards four types of aflatoxins. Based on this in silico results, it is evident that the both the lipoteichoic acid (LTA) and wall teichoic acid (TA) in the cell wall of probiotic organisms is responsible for its binding against aflatoxins.

The diseases in poultry cause huge losses in the form of mortality in acute infections or as substandard performance due to chronic illness. Biosecurity and vaccination are considered as two important primary strategies for disease prevention in poultry. On the other hand, breeding for disease resistance is an alternate strategy to combat the damages of diseases. Although, attempts were initiated to develop disease resistant poultry by breeding almost a century before, this branch of science renewed the interest among scientists because of catastrophic emerging and reemerging diseases like Avian influenza. It has proven over a period of time that poultry  exhibits genetic resistance to viral diseases like avian leukosis complex, Marek’s disease, avian influenza and Newcastle disease, bacterial disease like salmonellosis and may parasitic infestations. The key genes responsible for resistance to specific diseases have also been demonstrated. The breeding attempts for developing disease resistant poultry has yielded positive results with varying degree of success. The advent of sophisticated molecular methods like genomic selection using highdensity SNP chips, RNA-seq technique and identification of key marker genes and transgenesis could complement the conventional breeding methods to a larger extent in developing disease resistant poultry.

In recent times drug repurposing has gained interest over the traditional drug discovery due to reduction in time and cost of development of new drug. Drug repurposing approach has given promising drug candidates for various viral diseases like COVID 19, Ebola, Zika, Dengue, Influenza, HIV, Herpes, etc. Ontarget and off-target are the two basic strategies of drug repurposing. Macrolide, Artemisinin, Quinoline antiparasitic drugs are some of the drugs repurposed against cancer and drugs like thalidomide are repurposed against COVID-19 infection. Repurposing of veterinary drugs like ivermectin, levamisole and benzemidazole group of antiparasitic drugs are also under consideration. This review elaborates repurposing of antihypertensive drugs like angiotensin- converting enzyme inhibitors (ACEI), angiotensin-receptor blockers (ARBs), β-blockers as anti- neoplastic drugs, anti-diabetic drugs against Alzheimer’s disease, fluorophenyl benzimidazole (FPD) as antihypertensive drug, thalidomide against COVID-19 infection, levamisole as antineoplastic drug, benzimidazole as anti-cryptococcal drug and some other new drugs. Usage of in silico techniques and pharmacophore modeling strategies can further accelerate the process of drug repurposing. The drug repurposing strategies significantly minimize research and development costs, provide greater chances of success, shorter research time and lower investment risk.

The present study was undertaken to evaluate the effect of different levels of dried capsicum powder on the quality characteristics of chicken koftas. The capsicum dried powder was incorporated at three different levels viz. 2, 4 and 6% in the formulation. The products were analyzed for various physicochemical and sensory attributes. The pH, emulsion stability (83.56±0.011) (%), cooking yield (81.12±0.011) (%), crude protein, crude fat and total ash contents of the products showed significant (P<0.05) decreasing trend with increase in levels of incorporation of dried capsicum powder. However, a significant (P<0.05) increase in the water holding capacity (%), moisture (67.10±0.008) and crude fibre (1.56±0.006) contents of the chicken koftas was observed with increasing levels of incorporation. Sensory evaluation revealed that koftas prepared with 4 per cent capsicum dried powder had superior scores (P<0.05) compared to 2 and 6 per cent. Hence, incorporation of dried capsicum powder at 4 per cent level in chicken koftas was considered to be optimum. (Include some values of important findings). 

An one and half year old Jersey crossbred heifer was presented to the Veterinary Clinical Complex, Veterinary College and Research Institute, Namakkal with the history of recurrent bloat, copious salivation, severe respiratory distress and abdominal distension. Under local infiltration with 2% lignocaine hydrochloride, trocharization was performed on left paralumbar fossa using trochar and canula to relieve the gas from the rumen. Palpable hard mass noticed in the caudal cervical esophagus and attempt was made to retrieve with the hand through the oral cavity was unsuccessful. Oesophagogram revealed barium stasis on ventral aspect between 4 th and 5 th cervical vertebra. As the obstruction could not be relieved by passing a probang, cervical oesophagotomy was performed and foreign body (Trichobezoar) was retrieved without any complications.

Contamination of locally fermented cow milk (Nono) by pathogenic bacteria constitute a major public health problem. This was because contaminated milk was a good medium that can support the growth and propagation of microbial pathogens. This study was designed to assess the bacteriological quality of locally fermented cow milk consumed in Maiduguri, northeastern Nigeria. Totally, forty (n = 40) samples of fresh, locally fermented cow milk (Nono) were collected and used in this study. Ten (10) milk samples each were collected from four randomly selected selling points (Monday Market, Custom Market, Kasuwan Shanu and Tashan Bama). The bacteriological quality of each milk sample were analysed using standard procedures for isolation, identification and enumeration of pathogenic bacteria. The mean total plate count ranged from 1.44x10 8 CFU/mL to 10.31x10 8 CFU/mL, while the mean total coliform count range from 0.57x10 8 CFU/mL to 11.17x10 8 CFU/mL. Statistically, there was a significant difference (p<0.05) in the mean total plate count and coliform count of milk samples collected from the four sampling points.Bacteriological culture and biochemical identification of all the isolates revealed Escherichia coli29(72.5%), Klebsiella specie3(7.5%), Salmonella specie 2(5%), Staphylococcus aureus 14(35%) and Streptococcus specie15(37.5%) respectively. All the results were above the acceptable limits (1.0 to 3.0 x 10 5 CFU/mL for total plate count and no coliform count per 100ml of milk sample) set by NAFDAC. Therefore the Nono products consumed in Maiduguri was not safe and wholesome for public consumption. Hence, the need to ensure the maintenance of standard hygienic protocols during the collection, storage, processing and marketing of locally fermented cow milk (Nono) in order to minimize microbial contamination.

A biological trial was conducted to study the effect of multi enzyme supplementation on ileal digestibilities of dry matter (DM), crude protein (CP), ether extract (EE), phytate phosphorus (PP) and non-starch polysaccharides (NSPs) in terms of neutral detergent fibre (NDF), acid detergent fibre (ADF), hemicellulose and cellulose in broilers for a period of 0-6weeks. The broilers used in this trial were fed diets supplemented with enzyme at 0, 250, 500, 750 and 1000 g/ton of feed with a proportionate reduction in metabolizable energy (ME-1.25, 2.5, 3.75 and 5 %), crude protein (CP-0.75, 1.5, 2.25 and 3 %), methionine + cytine (0.5, 1, 1.5 and 2 %) and available phosphorus (2.2, 4.4, 6.6 and 8.8 %). The level of individual enzyme per gram of multi enzyme supplement was cellulase 146 IU, xylanase 241 IU, pectinase 98 IU, protease 74 IU, amylase 778 IU and phytase 33 IU. The ileal digestibility was conducted on 6 th week of trial. The ileal DM digestibility (%) was significantly (p<0.01) increased in 750 g and 1000 g enzyme supplemented groups than other treatment groups. The increase in ileal DM digestibility was significantly (p<0.01) higher (6.2 %) in the group fed with 750 g enzyme supplementation than control. The digestibility of ileal crude protein (%) significantly (p<0.01) increased in 500, 750 and 1000 g enzyme supplemented groups than control. The increase in ileal protein digestibility was 12.20 % in 500 g/ton, 9.90 % in 750 g/ton and 10.12 % in 1000 g enzyme supplemented groups than control. However a non significant difference was observed in ileal EE digestibility in all treatment groups. The ileal phytate phosphorus digestibility significantly (p<0.01) increased in all the enzyme supplemented groups (33.69 % in 250 g/ton, 38.75 % in 500 g/ton, 39.53% in 750 g/ton and 42.11% in1000 g/ton) than control (31.71%). A highly significant (P< 0.01) increase in ileal neutral detergent fibre (NDF) and hemicellulose was observed in 500 to 1000 g enzyme supplemented groups than control. Similarly significant (P<0.01) increase in ileal acid detergent fibre (ADF) and cellulose digestabilities (%) were observed in all enzyme supplemented groups than control. It was concluded that the multi enzyme supplementation at minimum inclusion level of 500 g per ton of feed increased the ileal digestibilities of CP, PP, NDF, ADF, hemicelluloses and cellulose by 12.20 %, 18.17 %, 13.57 %, 55.63 % 12.77 % and 52.64 % respectively than control in broiler diet than the control diet in broilers.

The aim of this study was to evaluate two different superovulation protocols for quality embryo production. Donor animals were selected (Day 0) and a progesterone device was inserted. The superstimulatory treatment was initiated in day 7 (D7) with follicle stimulating hormone from porcine (FSHp) in eight decreasing doses each at 12 hours interval. Along with the fifth dose of FSHp, 500μg cloprostenol was administered. The progesterone device was removed 12h (Treatments P12) and 24 h after the first application of cloprostenol (Treatments P24). Twelve hours after the eighth dose of FSHp (D11) 25µg of Buserelin was administered and the inseminations were done after 12 and 24 hours. Embryos were collected in the forenoon of D18. P24 presented better results than the P12 treatment.