In the conditions of the Republic of Belarus there was studied the influence of electroactive solutions of anolyte neutral, catholyte alkaline and hypochlorite sodium on microbial flora of a gastro enteric path of calves and sheep. In course the realized research it was stated that more expressed action of anolyte neutral and hypochlorite sodium on beneficial microflora of animal intestines (namely, the decrease in quantity of some indexes) can probably be explained by an expressed antimicrobic action of the analyzed solutions. However, the quantitative changes occurring in composition of microbial flora were not so great and cannot cause radical changes of a microbial landscape of gastro-intestinal tract. Less expressed influence on microbial flora of intestines of calves and sheep rendered the solution of alkaline catholyte. Taking into consideration the expressed regenerative properties of the studied electroactive solution, it was possible to assume, that according to the mode of action of the preparation, its application will promote the increasing of protective forces of an organism without causing any radical changes of a microbial landscape of intestines of animals. The problem of influence of electroactive solutions on a microbial landscape of a gastro enteric tract of animals demands the further studying, however at the given stage it is possible to make a conclusion, that the quantitative changes of the microbial flora which were caused by application of the analyzed solutions, proved to be less fatal and did not render sharp negative influence on a microbial landscape as a whole. Taking into consideration data of the realized research it is possible to make a conclusion on possibility of application of the electro activated solutions of anolyte neutral, catholyte alkaline and hypochlorite sodium for treatment of gastro enteric tract diseases of agricultural animals.

In the conditions of the Republic of Belarus there was realized a complex of studies of quality swine slaughter products against the background of combine applications of the albuminous-vitamin-mineral additive Immovit and an extract of hill-growing saltwort for the preventive maintenance and treatment of a toxic dystrophy of liver. Research results showed the analysed preparations did not render negative influence on quality and safety of produced meat products. Against the background of application of the albuminous-vitamin-mineral additive Immovit in combination with an extract of hill-growing saltwort there was stated the improvement of swine slaughter product quality. In products from the animals which were administrated with a complex of examined preparations there was stated an optimized moisture content, the increasing of a relative biological value of a product (101,3-103,8%), and according to the indexes of bacterial safety the experimental pork considerably surpassed the meat indexes from animals of control groups. At the same time, in slaughter animal products of control groups there were revealed coliform bacillus bacteria.

In the conditions of the Republic of Belarus there were studied the anthelminthic properties of preparative forms of elecampane (Inula helenium) (herbal infusion, tincture, liquid and dry extracts). Research results showed that the analyzed preparative forms in the administrated doses possesed high therapeutic efficiency against strongyloidosis and strongylatosis of gastroenteric path of sheep. Thus, according to results of research it was established, that the highest therapeutic effect rendered herbal infusion of elecampane in a dose of 6 ml/kg live weight once a day three days continuously; and the antiparasitic efficiency was 60%. Application of elecampane tincture in a dose of 1 ml/kg live weight once and 0,5 ml/kg of live weight twice rendered the 100% therapeutic effect. Administration of a liquid extract of elecampane in a dose of 0,2 ml/kg live of weight once and 0,1 ml/kg of live weight twice rendered 100% therapeutic effect. Application of elecampane dry extract in a dose of 30 mg/kg of live weight once and 25 mg/kg of live weight twice rendered 100% therapeutic effect.

In the conditions of the Republic of Belarus there were studied the aetiology factors in development of dermatoses of productive cows taking into account the hygienic aspects. Structural defects of floors of cattle livestock buildings in animals of an experimental group promoted higher (on 35%) development of mattery dermhelminthiasis of distal areas of hindlegs in comparison with animals of a control group. Occurrence of skin dermhelminthiasis, especially in distal areas of hindlegs, was caused by various primary traumas of soft parts with the subsequent introduction into them of pathogenic microbial flora. The imperfect design of floors, an unsatisfactory microclimate in cow cattle houses, hypodynamia in the absence of constitutional walk made the preconditions for it. The reasons of purulent dermatosis of cows were two interconnected etiological factors: mechanical damages of tissues and development of a surgical infections in affected areas against the background of unsatisfactory microclimate that led to decrease in dairy efficiency on 4,51%. Therefore in a complex of the actions directed towards the preventive maintenance of surgical diseases, it is necessary to include the strict control over designing, building and operation of cattle-breeding premises, traumatism prevention, creation of an optimum microclimate and observance of zoohygienic norms of cattle maintenance.

In the conditions of the Republic of Belarus taking into consideration the hygienic aspects there were studied the aetiological factors in dermatosis development in productive cows. As a result of realized research it was established that aetiology of skin diseases in the area of a mammary gland were traumas, and following affects were more often marked: skin rhagades of mammillars; wound in the area of a mammary gland and mammillars; fistulas of milk tank vessels; and also sporadic damages of sphincter muscle of teat canal caused by machine milking. This in its turn gives made it possible to consider, that traumas of various character were a contributing factor for occurrence of udder garget - mastitis. In course of the realized analysis there was proved a high therapeutic efficiency of 1% aethonium gel for the treatment of various traumas of mammary gland and udder mammillars of cows. Clinical recovery of animals after administration 1% aethonium gel was stated on 3,2 days earlier, than after administration of Burenushka cream in the postoperative period. Healing and restoring action of 1% aethonium gel for udder tissues was proved by changes in number of somatic cells in milk. The quantity of somatic cells in 7 days after administration of 1% aethonium gel came back to the level which was typical healthy animals, while in the control group the quantity of somatic cells per 1 ml of milk did not decrease essentially.

In the conditions of the Republic of Belarus there were determined the parameters of acute and subacute toxicological characteristics of the developed in the Vitebsk State Academy of Veterinary Medicine anthelmintic preparations of durable action Febolvetum-О for control of sheep strongylatosis and Febolvetum for control of strongylatosis of cattle young stock. Data on determination of toxicological parameters of the prolonged action bolus were presented. Research results showed that the preparations did not render negative influence on laboratory animals (white mice). According to the parameters of acute oral toxicity the Febolvetum was qualify as the third hazard class. In accordance with the results of study of subacute toxicity parameters of the preparations, it was concluded, that in the conditions of free feeding of Febolvetum boluse in combination with forages in course of 30 days in doses of 200 mg/kg; 150 mg/kg; 100 mg/kg of body weight in animals there were found no signs of intoxication; there were not stated any is not fixed deviations in physiological state; and were stated no mice death.

In the conditions of the Republic of Belarus there were studied biochemical indexes of calf blood serum against the background of application of probiotic preparations Bilavet C. Results of research showed that administration of probiotic preparations from the first day till the six day and from the fourteenth day till the nineteenth day of calf life with the preventive purpose rendered the simulative influence on indexes of natural resistance, which were accompanied with the increasing of total protein quantity in blood on 2,9-5,9%, as well as the increasing of protein fractions, in particular, globulin-rich fraction on 4,2-6,4%. Administration of probiotic preparation Bilavet С to calves rendered the positive influence on blood biochemical indexes, promoted the uptaking and better accumulation of mineral substances: content of crude calcium, inorganic phosphorus, magnesium, iron increased on 15,3%, 10,5%, 13,2% and 3,6%, respectively.

In the conditions of the Republic of Belarus there were studied circadian rhythms of some haemotological and biochemical blood indexes of clinically healthy calves and calves with a respiratory syndrome. There was analyzed the efficiency of administration a new complex mineral preparation CMP for correction of internal desynchronoses in complex therapy of calves with respiratory pathologies. Diseases of calves with a respiratory syndrome were accompanied by infringements of circadian fluctuations rhythm (internal desynchronosis) of haemotological and biochemical blood indexes. Application of an antimicrobial preparation Ampicillin for treatment of respiratory diseases of calves promoted the recovery of calves. Introduction of CМP preparation into therapeutic regimen of calves with respiratory syndrome proved to be rather effective; it promoted the correction of metabolic desynchronoses which accompanied the basic disease. Combined application of CМP and Ampicillin made it possible to speed up the clinical recovery of calves and on 30% to prevent animal mortality.

In the conditions of the Republic of Belarus there was studied a comparative efficacy of methods of drug administration for diseased animals with respiratory diseases. It was stated that enteral (internal) administration of Tromexin in a complex therapy of calves with respiratory pathology possesses rendered low therapeutic efficacy and could have a lethal outcome. Parenteral (intramuscular) administration of Enrotil and Dexafort for a complex therapy of calves with respiratory pathology rendered a moderate therapeutic efficacy and could lead to animal's state improvement. Parenteral (intravenous) administration of hypertonic solutions of norsulfazol, calcium chloride, sodium chloride and glucose in complex therapy of calves diseased with a respiratory pathology proved to render a high therapeutic efficacy and may lead in a complete clinical recovery.

In the conditions of the Republic of Belarus there was realized the evaluation of genetic inheritance indexes of producing bulls at a cattle breeding enterprise in Belarus depending on a selection source (in accordance with an average productivity of female ancestors) in order to use them properly for the increasing of genetic potential of black-and-white Belarusian cows in Gomel region. The carried out analysis allowed to draw a conclusion, that bulls of national breeding lines according to the indexes of cow milk yields concede foreign bulls, i.e. delivered of Sweden on 2744 kg of milk or on 27,5% and from Russia and Hungary - on 1272-2906 kg of milk or 12,7-29,1% (Р less than 0,001). In accordance with butter-fat yielding capacity of bull mothers obtained at breeding farms of Belarus and in accordance with groups delivered from the other countries there were stated no essential distinctions (0,05). Butter-fat yielding capacity percentage of bull mothers varied within 3,99-4,10%. However, the yield of dairy fat per lactation the difference was in favour of bull mothers delivered from Sweden (114 kg or 27,9%) at P less than 0,001. Distinctions on milk producing ability of bull mothers from various cattle breeding enterprises of Belarus were revealed. It was established, that at mothers of bulls delivered from Hungary the variability of milk yield was the highest (3032 kg or 23%). Low variability indexes of milk yield and butter-fat yielding capacity percentage was typical for bull mothers of the Belarusian selection. The standard deviation at them made 872 kg of milk yield with 9% variability coefficient, and 0,03% - for butter-fat yield and 7% respectively. Variability on all indicators of dairy efficiency of bull mothers from various cattle breeding enterprises of Belarus in most of the cases was low - from 2,3 to 13%.