Biochemical and antimicrobial susceptibility tests were conducted on 40 strains of Pseudomonas aeruginosa which originated from diseased chicken. An extensive study of the biochemical properties revealed that the tested strains can be identified with Pseudomonas aeruginosa. Antibiogram showed that all the strains were susceptible to gentamicin, colistin and amikacin but resistant to nitrofurantion, trimethoprim plus sulfamerthoxasole, ampicillin, methicillin and kanamycin and had varying degrees of resistance to other antimicrobials including carbenicillin, sulfomamides, neomycin, streptomycin, tetracycline and chloramphenicol. Three of the most frequent resistance patterns observed were FM (Nitrofurantoin) SXT (Sulfamethoxasole) AM (Ampicillin) ME (Methicillin) KM (Kanamycin) CM (Chloramphenicol) TC (Tetracycline) SM (Streptomycine) NE (Neomycine) SSS Pattern, FM SXT AM ME KM CM TC SM NE SSS CB (Carbenicillin) Pattern and FM SXT AM ME KM CM TC SM Pattern, and these resistance patterns contained 72.5% of the tested strains

This experiment was conducted to determine the effect of hypobaric hypoxia on PCV (packed cell volume), Hb conc. (hemoglobin concentration), RBC No. (red cell number) and red cell GSH (levels of reduced glutathione) and DPG (diphosphoglycerate) in the rabbit. There was a significant rise in all the parameters measured except DPG which did not change during and/or after the hypobaric hypoxia

This experiment was done to estimate the blood urea nitrogen and serum creatinine concentrations in renal dysfunction which was experimentally induced with reduction in renal mass in dogs. During the experiment, blood urea nitrogen and serum creatinine concentrations showed no variance in dogs with 50% reductions in renal mass, but these values were remarkably increased in dogs with 75% reductions in renal mass. It was considered that 755 reductions in renal mass was applicable as experimental models for renal dysfunction

This study was undertaken to clarify the histopathological changes of pigs naturally infected with hog cholera. Vascular cuffing of the brain was observed in about 97% of the natural cases and all of the experimental cases. Electron microscopic findings on cuffed blood vessels of the brain were endothelial cellular degeneration and infiltration of pleomorphic lymphoid cells. In the rabbits dosed with tissue suspension of the lymphoid organs and isolated hog cholera virus, high body temperature and vascular cuffing of the brain were more significant in pre-injected cases with indian ink

This study was performed to clarify the clinical signs of macroscopical lesions of pigs naturally infected with hog cholera. There was clinical and macroscopical observation on the natural cases of hog cholera and experimental cases inoculated with ALD virus and isolated virus strains. In the clinical inspection of the natural cases, diarrhea (73.1%), blotching of ear (50.0), conjunctivitis (32.7%) and dyspnea (30.8%) were observed. Dyspnea, constipation and erythema of skin were observed mainly in the experimental cases, however, staggering and conjunctivitis in pigs infected with ALD virus were found and convulsion and hemorrhage of skin of pigs infected with isolated virus were seen, respectively. The gross lesions of natural cases were hemorrhage of lymph node (82.5%), pneumonia (55.0%), gastritis and hemorrhage (52.5%), cardial hemorrhage (40.0%) and renal petechiation (37.5%), while in the experimental cases, hemorrhage of lymph node, pneumonia, gastritis and hemorrhage, enteritis and hemorrhage of large intestine and splenic infarction were seen mainly

The presence of fibrinous thrombi in the blood vessels of multiple organs was observed in chickens which died within approximately 3 days post inoculation. The density of fibrinous thrombi (i.e., the number of thrombi per section) was greatest in the lung, followed by spleen, kidney, liver and heart. The cause of death of the chickens after infection with acute fowl cholera was probably due to an endotoxin (septic) shock accompanied with DIC in multiple organs

3,354 fattening pigs were examined. Gross pathologic alterations of the stomach were classified as normal, with epithelial change, erosion, ulcer and scar formation. In the seasonal prevalence of gastric ulceration, severe ulceration with erosion was shown during autumn and winter, whereas mild ulceration was mainly shown during spring and summer. Of the 3,354 pigs examined, 20.7% were found to be normal. Of the rest, 40% had epithelial changes, followed by erosion (24.7%), ulcer (13.6%) and scar formation (0.9%), respectively. In the prevalence of ulcers in the different regions of the stomach, the fundic region had the highest rate (61.6%) of ulceration, followed by cardiac (21.7%), esophageal (15.0%) and pyloric region (1.7%). The principal gross changes were severe epithelial changes with keratotic proliferation in the esophageal region, and in the fundic region, severe folding of the stomach wall was covered with bloody mucous exudates. Main histopathological changes were inflammatory cell infiltrations in most cases, hemorrhages in acute ulcers and prominent proliferation of granulation tissues in chronic ulcers