In the conditions of the Republic of Belarus there was determined of a dose of input and efficiency of feeding with rape oil cake and protein meal produced on the basis of a new rape (Brassica napus) variety Yavar as a part of a mixed fodder KR-2 in diets of young stock of cattle. Rape oil cake and protein meal with the content of 1,4-1,9% glucosinolates and 27-30 mcM per 1 kg of a dry matter of erucidic acid can be included into composition of the mixed fodder КR-2 for bull calves in a dose up to 20% on weight. Feeding with the mixed fodders КR-2 with inclusion of rape oil cake and protein meal made it possible to receive daily average weight gain of calves at a level of 827-906 gram at expenses of forages of 5,4-5,9 forage units per 1 kilogram of a weight gain. It was caused by cheaper rape forages. In course of the study there was analyzed the chemical composition of rape oil cake and protein meal; indexes of rumen digestion of experimental bull calves; morphological and biochemical blood structure; changes of body weight; daily average weight gain and expenses for forages.

In the conditions of the Republic of Belarus there was determined the genetic structure of population of breeding boars, sows, replacement and crossbred stores in accordance with RYR1 gene which was connected with stress resistance. Also, there was analyzed the influence of genetic polymorphism of this gene on meat productivity. In course of the study there was presented a genetic structure of breeds according to gene loci RYR1. There was analyzed the frequency of occurrence of alleles and genotypes in accodance with gene loci RYR1 of breeding boars and replacement stores of different lines. There were showed the indexes of meat productivity and acid capacity of purebred and crossbred stores with different RYR1 gene genotypes. As a result of study there was revealed a rather high level of presence of allele RYR**n in all sex and age specific groups of Belarusian meaty breed (21%) and crossbred stores of Large white x Belarusian meaty breeds (40%). But in the experimental group of three-breed cross breeds (Large white x Belarusian meaty) x Duroc there was not stated the presence of allele of malignant hyperthermia. High level of RYR**n allele presence in populations of meaty breeds and their crossbreeds proved the necessity of obligatory genetic control of pedigree as well as imported animals by means of DNA diagnostic.

In the conditions of the Republic of Belarus there was realized an ecological monitoring of sources of water supply in the conditions of a swine breeding complex and adjoining settlements. There was studied the influence of a large swine breeding complex on water quality of closed type water sources. There was marked a microbial contamination of water depending on remoteness of animal breeding object and season of a year. There were determined the seasonal changes of physical properties, chemical and bacteriological composition of water used for swine breeding. There were noted changes in water quality in the process of its flow from the point of water inlet up to the place of its consumption. Results of influence of improved water on piglets were presented. There was studied the possibility of improvement of water quality by means of its treatment with solution of potassium hypermanganate (0,01%) which made it possible to increase average daily live weight gain of piglets. In course of the study there was realized the analysis of protein spectrum of blood serum of piglets; dynamics of body weight and average daily weight gain of experimental piglets.

In the conditions of the Republic of Belarus there was analyzed the influence of diets with different ratio of degradable and by-pass proteins on morphological and biochemical blood composition and productivity of bulls of black-and-white breed. In course of the study there was analyzed the average feeding diet of young stock of cattle in accordance with actually eaten fodders; morphological and biochemical blood indexes; live weight and average daily weight gain; results of a control slaughter. Research results showed the feeding at the finishing period of fattening-off with different ratios of degradable and by-pass proteins in ratio 60-65:40-35 made it possible to obtain 1049-1078 grams of live weight gain of bulls per day in the conditions of fodder expenses of 8,22-8,40 fodder units per 1 kilogram of weight gain. As a result the energy of weight gain was 20,1-21,2 mJ. Conversion of metabolizable energy at weight gain stage was at the level 20,4-21,8%. Expenses of metabolizable energy per 1 mJ at weight gain were 4,83-5,05 mJ, and prime cost of body weight gain lowered on 5% in comparison with control.

In the conditions of the Republic of Belarus there was analyzed the efficiency of application of a whole milk substitute Biomilk-11 and feed additive SFDK-1 (biologically active enzymatic feed additive) for breeding of young stock of cattle, by an example of calves of black-and-white breed. In course of the study there was analyzed the composition of the feed additive SFDK-1 (weight fraction of dry matter; weight fraction of protein; content of amine nitrogen; cellulose fiber activity) as well as the physical and chemical indexes of the whole milk substitute Biomilk-11 (moistness; crude protein; crude fat; crude fibre). There were presented indexes of live weight gain of experimental and control calves as well as the dynamics of average daily weight gains in experimental group. Research results proved the efficiency of application of both additive for calves feeding.

In the conditions of the Republic of Belarus there was determined the efficiency of application of different levels of vitamins and trace elements in feeding of servicing bulls. In course of the study there was analyzed the influence of different levels of supply of servicing bulls with vitamins A, D, E and trace elements (copper; zinc; manganese; iron; cobalt; selenium) on their reproductive ability. On the basis of the experiment there was calculated the economic efficiency of application of the developed vitamin and mineral additive. Research results showed that application of the developed protein and mineral additive in diets of servicing bulls in winter and summer periods made it possible to increase the ejaculate volume on 7,4% and 12,4% (P less than 0,05), sperm activity on 6,7 % (P less than 0,05) and 7,3% (P less than 0,01), concentration of spermium in ejaculate on 6,3% and 7,8% (P less than 0,05). Also, it promoted the lowering of percentage of defective sperm doses.

In the conditions of the Republic of Belarus there was studied the pathology and biology of cattle capillariasis. Capillariosis invasion rendered a substantial invasion on blood morphological composition which was revealed in lowering of erythrocytes and hematoglobulin, as well as in increasing of leukocytes quantity. There was noted the lowering of the natural resistance and immune reactivity. There were stated substantial deviations in protein metabolism which was expressed in lowering of total protein, quantity of albumins, changing of albumin and globulin coefficient, increasing of globulins. In the conditions of blood biochemical analysis of infesrated animals there was stated a disorder of vitamin and mineral metabolism; increasing of alanine aminotransferase and aspartate aminotransferase enzymes activity. Development of Capillaria bovis was realized in a direct line. In the natural habitat development of Capillaria bovis eggs varied from two up to three months.

In the conditions of the Republic of Belarus there was analyzed the efficiency of bactericidal action of tartaric acid aerosol for air sanitation of poultry buildings and increasing of broiler chickens viability. The bactericidal action was analyzed by the example of Staphylococcus aureus, Eschericia coli and Proteus vulgaris. In course of study there were analyzed biochemical indexes of blood and blood serum, lymphoid tubercle in proper mucous plate of trachea of broiler chickens after 6-time treatment with tartaric acid and Ekotsid C preparation. Research results showed that the analysed preparations did not render negative influence on metabolic indexes of broiler chickens and increase poultry viability. Application of tartaric acid did not cause pathomorphologic changes in tissues and organs of birds, stimulated the active proliferation of leucocytes in immune system organs (thymus gland; spleen; and lymphoid tissue).

In the conditions of the Republic of Belarus there was realized creation and evaluation of growth activity of serum and albuminous nutritional media. In the experiment there were used of 6 pathogenic strains: Leptospira pomona; Leptospira tarassovi; Leptospira grippothyphosa; Leptospira icterrohaemorragia; Leptospira conicola; Leptospira sejroe. For the Leptospira cultivation there were used the following media: serum-supplemented vitaminized medium on the basis of buck serum; serum-supplemented medium with a growth factor; serum-supplemented vitaminized medium with antlbody biosynthesis growth factor; semisynthetic Russel's medium in modification of V.I. Sitkov. Research results showed that the albuminous nutritional medium provided an intensive accumulation of Leptospira of all tested serogroups of Leptospira, but was suitable only for single bacterial inoculation. For the secondary hatching the albuminous media was unsuitable as it lowered the antigenic activity of Leptospira.

In the conditions of the Republic of Belarus by means of application of a scanning electron microscopy there was realized a morphological assessment of the efficiency of mono- and associated antiviral vaccines. It is shown, that analyzed biological preparations invoke in poultry a number of structural disorders among which it is possible to mention both immunomorphological changes, and pathomorphological processes. The highest reactogenicity was showed by of monovaccines against infectious bronchitis (produced by Research Institute of Animal Protection, Russia); infectious laryngotracheitis (Institute of Experimental Veterinary of S.N.Vyshelesskij, Belarus); and also an associated vaccine against infectious bronchitis, infectious bursal disease and Newcastle disease (Research Institute of Animal Protection, Russia). These vaccines caused essential structural disorders in tissues at a place of administration, liver and kidneys. Administration of the vaccine against infectious bursal disease and associated vaccines against infectious bronchitis, infectious bursal disease, infectious laryngotracheitis and Newcastle disease (Institute of Experimental Veterinary of S.N.Vyshelesskij) strengthened the processes of lymphatization in fabricic bursa. All studied biological products caused activization of morphological reorganization of immune apparatus of a spleen and did not render essential influence on thymus structure. | С использованием сканирующей электронной микроскопии проведена морфологическая оценка эффективности моно- и ассоциированных противовирусных вакцин. Показано, что указанные биопрепараты вызывают в организме птиц ряд структурных нарушений, среди которых можно выделить как иммуноморфологические изменения, так и патоморфологические процессы. Наибольшую реактогенность проявляли моновакцины против инфекционного бронхита кур (ФГУ ВНИИЗЖ, Россия), инфекционного ларинготрахеита (ИЭВ им. С.Н. Вышелесского), а также ассоциированная вакцина против ИБК, инфекционной бурсальной болезни и болезни Ньюкасла (ФГУ ВНИИЗЖ, Россия), которые вызывали существенные структурные нарушения в ткани на месте введения, печени и почках. Использование вакцины против ИББ и ассоциированной вакцины против ИБК, ИББ, ИЛТ и БН (ИЭВ им. С.Н. Вышелесского) усиливало процессы лимфатизации в фабрициевой бурсе. Все изучаемые биопрепараты вызывали активизацию морфологической перестройки иммунного аппарата селезенки и не оказывали существенного влияния на структуру тимуса.