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Assessment of polybrominated diphenyl ethers (PBDEs) in serum from the Korean general population 全文
2012
Kim, Jongchul | Kang, Jung-Ho | Park, Hyokeun | Baek, Song-Yee | Kim, Yang-ho | Chang, Yoon Seok
In 2009 and 2010, 720 serum samples were collected from non-occupationally exposed study participants at four Korean locations and monitored for the presence of 27 polybrominated diphenyl ether (PBDE) congeners. The median concentrations of Σ₂₇PBDEs (the sum of 27 congeners) and Σ₃–₇PBDEs (the sum of tri- to hepta-BDE congeners) were 6.04 and 4.97 ng/g lipid, respectively. The most abundant congener detected in serum samples was BDE-153, followed by BDE-47 and BDE-99. The median value of Σ₃–₇PBDEs was similar to the median values observed in Asia and Europe, but much lower than that observed in North America. Some significant differences, based on geographic region and sex, were observed. We also observed a positive increase of BDE-153 with regard to age. In addition, we estimated the daily exposure to PBDEs from previously published reports of PBDE concentrations in food and dust, and determined the individual contributions of a variety of sources.
显示更多 [+] 显示较少 [-]Levels and sources of brominated flame retardants in human hair from urban, e-waste, and rural areas in South China 全文
2011
Zheng, Jing | Luo, Xiao-Jun | Yuan, Jian-Gang | Wang, Jing | Wang, Yu-Tao | Chen, Shen-Jun | Mai, Bi-Xian | Yang, Zhong-Yi
Human hair and indoor dust from urban, e-waste, and rural areas in south China were collected and analyzed for brominated flame retardants (BFRs). BFRs concentrations in hair from occupational e-waste recycling workers were higher than those from non-occupational exposed residents in other sampling areas. Polybrominated diphenyl ethers (PBDEs) and decabromodiphenyl ethane (DBDPE) are two major BFRs in hair samples. The PBDE congener profiles in hair from the e-waste area are different from those from urban and rural areas with relatively higher contribution of lower brominated congeners. DBDPE, instead of BDE209, has become the major BFR in non-e-waste recycling areas. Significant correlations were found between hair level and dust level for DBDPE and BTBPE but not for PBDEs. The different PBDE congener profiles between dust and hair may suggest that exogenous exposure to the PBDE adsorbed on dust is not a major source of hair PBDEs.
显示更多 [+] 显示较少 [-]Prenatal methylmercury exposure through maternal rice ingestion: Insights from a feasibility pilot in Guizhou Province, China 全文
2013
Rothenberg, Sarah E. | Yu, Xiaodan | Zhang, Yumei
Maternal hair and blood were investigated as biomarkers for prenatal methylmercury (MeHg) exposure among seventeen mothers recruited at parturition in Wanshan, Guizhou Province, China, where rice ingestion was the primary MeHg exposure pathway and atmospheric mercury (Hg) levels were elevated. For all three trimesters (n = 51), hair total Hg (THg) and MeHg concentrations ranged from 0.27 to 4.9 μg/g (median: 0.96 μg/g) and 0.077 to 2.3 μg/g (median: 0.43 μg/g), respectively, while blood THg levels ranged from 1.7 to 11 μg/L (median: 3.0 μg/L, n = 17). Despite adequate hair washing procedures, median %MeHg (of THg) was 37% (range: 14–89%, n = 51), indicating exogenous inorganic Hg(II) contamination or incorporation of elemental Hg (Hgo) into the hair shaft were important. Rice MeHg levels (n = 17) were highly correlated with blood THg (r2 = 0.66) compared to hair MeHg (r2 = 0.31) (when variables were log10-transformed), suggesting blood THg was a more preferable biomarker for prenatal MeHg exposure within this population.
显示更多 [+] 显示较少 [-]Assessing mixed trace elements in groundwater and their health risk of residents living in the Mekong River basin of Cambodia 全文
2013
Phan, Kongkea | Phan, Samrach | Huoy, Laingshun | Suy, Bunseang | Wong, Ming Hung | Jamal Hisham Hashim, | Mohamed Yasin, Mohamed Salleh | Aljunid, Syed Mohamed | Sthiannopkao, Suthipong | Kim, Kyoung-Woong
We investigated the potential contamination of trace elements in shallow Cambodian groundwater. Groundwater and hair samples were collected from three provinces in the Mekong River basin of Cambodia and analyzed by ICP-MS. Groundwater from Kandal (n = 46) and Kraite (n = 12) were enriched in As, Mn, Ba and Fe whereas none of tube wells in Kampong Cham (n = 18) had trace elements higher than Cambodian permissible limits. Risk computations indicated that 98.7% and 12.4% of residents in the study areas of Kandal (n = 297) and Kratie (n = 89) were at risk of non-carcinogenic effects from exposure to multiple elements, yet none were at risk in Kampong Cham (n = 184). Arsenic contributed 99.5%, 60.3% and 84.2% of the aggregate risk in Kandal, Kratie and Kampong Cham, respectively. Sustainable and appropriate treatment technologies must therefore be implemented in order for Cambodian groundwater to be used as potable water.
显示更多 [+] 显示较少 [-]Global climate change: Impact of diurnal temperature range on mortality in Guangzhou, China 全文
2013
Yang, Jun | Liu, Hua-Zhang | Ou, Chun-Quan | Lin, Guo-Zhen | Zhou, Qin | Shen, Gi-Chuan | Chen, Ping-Yan | Guo, Yuming
Diurnal temperature range (DTR) is an important meteorological indicator associated with global climate change, but little is known about the effects of DTR on mortality. We examined the effects of DTR on cause-/age-/education-specific mortality in Guangzhou, a subtropical city in China during 2003–2010. A quasi-Poisson regression model combined with distributed lag non-linear model was used to examine the effects of DTR, after controlling for daily mean temperature, air pollutants, season and day of the week. A 1 °C increase in DTR at lag 0–4 days was associated with a 0.47% (95% confidence interval: 0.01%–0.93%) increase in non-accidental mortality. Stroke mortality was most sensitive to DTR. Female, the elderly and those with low education were more susceptible to DTR than male, the youth and those with high education, respectively. Our findings suggest that vulnerable subpopulations should pay more attention to protect themselves from unstable daily weather.
显示更多 [+] 显示较少 [-]Associations of prenatal exposure to phenols with birth outcomes 全文
2013
Tang, Rong | Chen, Min-jian | Ding, Guo-dong | Chen, Xiao-jiao | Han, Xiu-mei | Zhou, Kun | Chen, Li-Mei | Xia, Yan-kai | Tian, Ying | Wang, Xin-ru
Many phenols are known to mimic or antagonize hormonal activities and may adversely affect fetal growth. A study of 567 pregnant women was conducted to investigate the relationship between prenatal phenol exposure and birth outcomes, including birth weight, length, and gestational age. We measured the concentrations of bisphenol A, benzophenone-3, 4-n-octylphenol and 4-n-nonylphenol in maternal urine and examine their association with birth outcomes. Categories of urinary benzophenone-3 concentration were associated with decreased gestational age in all infants (p for trend = 0.03). Between middle and low exposure groups, we also found bisphenol A was negatively associated with gestational duration (βadjusted = −0.48 week; 95% confidence interval: −0.91, −0.05). After stratification by gender, we found the consistent results in infant boys with those in all infants, but we did not observe significant association for girls. In conclusion, we found prenatal phenol exposure was sex-specifically related to birth outcomes.
显示更多 [+] 显示较少 [-]High levels of DDT in breast milk: Intake, risk, lactation duration, and involvement of gender 全文
2012
Bouwman, Hindrik | Kylin, Henrik | Sereda, Barbara | Bornman, Riana
We investigated presence and levels of DDT in 163 breast milk samples from four South African villages where, in three of them, malaria is controlled with DDT-sprayed indoors. Mean ΣDDT levels in breast milk were 18, 11, and 9.5 mg/kg mf (milk fat) from the three DDT-sprayed villages, respectively, including the highest ΣDDT level ever reported for breast milk from South Africa (140 mg/kg mf). Understanding the causes for these differences would be informative for exposure reduction intervention. The Provisional Tolerable Daily Intake (PTDI) for DDT by infants, and the Maximum Residue Limit (MRL) were significantly exceeded. DDT had no effect on duration of lactation. There were indications (not significant) from DDT-sprayed villages that first-born female infants drink milk with more ΣDDT than first-born male infants, and vice versa for multipara male and female infants, suggesting gender involvement on levels of DDT in breast milk – requiring further investigation.
显示更多 [+] 显示较少 [-]Associations between standardized school performance tests and mixtures of Pb, Zn, Cd, Ni, Mn, Cu, Cr, Co, and V in community soils of New Orleans 全文
2012
Zahran, Sammy | Mielke, Howard W. | Weiler, Stephan | Hempel, Lynn | Berry, Kenneth J. | Gonzales, Christopher R.
In New Orleans a strong inverse association was previously identified between community soil lead and 4th grade school performance. This study extends the association to zinc, cadmium, nickel, manganese, copper, chromium, cobalt, and vanadium in community soil and their comparative effects on 4th grade school performance. Adjusting for poverty, food security, racial composition, and teacher-student ratios, regression results show that soil metals variously reduce and compress student scores. Soil metals account for 22%–24% while food insecurity accounts for 29%–37% of variation in school performance. The impact on grade point averages were Ni > Co > Mn > Cu ∼Cr ∼ Cd > Zn > Pb, but metals are mixtures in soils. The quantities of soil metal mixtures vary widely across the city with the largest totals in the inner city and smallest totals in the outer city. School grade point averages are lowest where the soil metal mixtures and food insecurity are highest.
显示更多 [+] 显示较少 [-]A comparison of submicrometer particle dose between Australian and Italian people 全文
2012
Buonanno, G. | Morawska, L. | Stabile, L. | Wang, L. | Giovinco, G.
Alveolar and tracheobronchial-deposited submicrometer particle number and surface area data received by different age groups in Australia are shown. Activity patterns were combined with microenvironmental data through a Monte Carlo method. Particle number distributions for the most significant microenvironments were obtained from our measurement survey data and people activity pattern data from the Australian Human Activity Pattern Survey were used. Daily alveolar particle number (surface area) dose received by all age groups was equal to 3.0 × 10¹⁰ particles (4.5 × 10² mm²), varying slightly between males and females. In contrast to gender, the lifestyle was found to significantly affect the daily dose, with highest depositions characterizing adults. The main contribution was due to indoor microenvironments. Finally a comparison between Italian and Australian people in terms of received particle dose was reported; it shows that different cooking styles can affect dose levels: higher doses were received by Italians, mainly due to their particular cooking activity.
显示更多 [+] 显示较少 [-]Assessing the relationship between global warming and mortality: Lag effects of temperature fluctuations by age and mortality categories 全文
2011
Yu, Weiwei | Mengersen, Kerrie | Hu, Wenbiao | Guo, Yuming | Pan, Xiaochuan | Tong, Shilu
Although interests in assessing the relationship between temperature and mortality have arisen due to climate change, relatively few data are available on lag structure of temperature–mortality relationship, particularly in the Southern Hemisphere. This study identified the lag effects of mean temperature on mortality among age groups and death categories using polynomial distributed lag models in Brisbane, Australia, a subtropical city, 1996–2004. For a 1 °C increase above the threshold, the highest percent increase in mortality on the current day occurred among people over 85 years (7.2% (95% CI: 4.3%, 10.2%)). The effect estimates among cardiovascular deaths were higher than those among all-cause mortality. For a 1 °C decrease below the threshold, the percent increases in mortality at 21 lag days were 3.9% (95% CI: 1.9%, 6.0%) and 3.4% (95% CI: 0.9%, 6.0%) for people aged over 85 years and with cardiovascular diseases, respectively. These findings may have implications for developing intervention strategies to reduce and prevent temperature-related mortality.
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