This investigation aims to study synoptic analysis in the dynamic structure accompanied by air pollution of extreme heat during July 2019 in the Yazd province. The time-series data analysis for the yearly surface air temperatures during the past two decades shows a significant peak surface air temperature in July 2019 in Yazd province. The long-term mean and anomalies of the daily basis (2001 to 2019) for the daily mean sea level pressure show a decrease in pressure with a maximum of about 6 hPa and an increase in geopotential height at 500 hPa with a maximum of about 20-30 gpm (geopotential meter), which has led to an increase in the average daily temperature of about 2 to 4 degrees Celsius. Also, showed high values for Ozone mass mixing ratio over the study area mostly over the west with a maximum of ~92 ppb in Yazd province on 1 July 2019. The AIRS (Atmospheric Infrared Sounder on NASA's Aqua satellite) data shows a positive trend (2003- 2019) for the total daytime Ozone column-averaged over the study area during July. Furthermore, the results of this work obtained from OMI satellite observation show a significant increase in the ultraviolet aerosol index (UVAI) during the study period time. This study shows the recent extreme weather changes in the study area which may be necessary for a better future forecast for heat warnings along with poor air quality and health risk when such events may happen in the future.