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Perinatal multiple exposure to neurotoxic (lead, methylmercury, ethylmercury, and aluminum) substances and neurodevelopment at six and 24 months of age
2014
Marques, Rejane C. | Bernardi, José V.E. | Dórea, José G. | de Fatima R Moreira, Maria | Malm, Olaf
We studied neurodevelopment in infants from two communities. Children living in the vicinity of tin-ore kilns and smelters – TOKS; n = 51) were compared to children from a fishing village (Itapuã; n = 45). Mean hair-Hg (HHg) concentrations were significantly higher in Itapuã children which received significantly (p = 0.0000001) less mean ethylmercury (88.6 μg) from Thimerosal-containing vaccines (TCV) than the TOKS children (120 μg). Breast-milk Pb concentrations were significantly higher in the TOKS mothers (p = 0.000017; 10.04 vs. 3.9 μg L−1). Bayley mental development index (MDI) and psychomotor development index (PDI) were statistically significant (respectively p < 0.0000001, p = 0.000007) lower for the TOKS children only at 24 months of age. Multivariate regression analysis showed that MDI was negatively affected by breast-milk Pb and by HHg. PDI was positively affected by breastfeeding and negatively affected by ethylmercury. Milestone achievements were negatively affected by breast-milk Pb (age of walking) and by HHg (age of talking).
显示更多 [+] 显示较少 [-]The past and future of fish consumption: Can supplies meet healthy eating recommendations?
2014
Thurstan, Ruth H. | Roberts, Callum M.
In many developed countries fish and shellfish are increasingly promoted as healthy alternatives to other animal protein. We analysed how much fish was available to UK and global populations after accounting for processing losses, and compared this to recommended levels of fish consumption. In 2012, UK domestic fish landings per capita fell 81% below the recommended intake, although declines were masked by increased imports and aquaculture from the 1970s onwards. Global wild fish supply per capita declined by 32% from its peak in 1970. However, overall fish supplies per capita increased by 10% over the same period due to rapidly expanding aquaculture production. Whilst aquaculture has so far prevented a downturn in global fish supplies, many developed nations continue to aspire to consume more fish than they produce. Until demand is balanced with sustainable methods of production governments should consider carefully the social and environmental implications of greater fish consumption.
显示更多 [+] 显示较少 [-]Food sources of arsenic in pregnant Mediterranean women with high urine concentrations of this metalloid
2014
Fort, Marta | Grimalt, Joan O. | Casas, Maribel | Sunyer, Jordi
Seafood consumption provides a significant amount of arsenic, although in its organic, nontoxic forms. Mediterranean populations may incorporate high levels of this metalloid as a consequence of seafood consumption. In the present study, the significance of this input among pregnant women from a Mediterranean city (Sabadell, Catalonia, Spain) is assessed. Total urinary arsenic was analyzed in 489 pairs of urine samples, corresponding to the 12th and 32th weeks of pregnancy. Association of arsenic content with seafood and other dietary items were studied. Geometric mean concentrations were 34 and 37 μg/g creatinine during the first and third trimesters, respectively. The observed concentrations were similar to those reported in studies from other Mediterranean countries. The differences between both periods were not statistically significant. The only dietary factor significantly and positively associated with total urinary arsenic in both series of samples was seafood, particularly lean fish. Moreover, lean fish consumption during both periods was found to be the main determinant for differences in levels of arsenic between the first and third trimesters, which confirms the association between high levels of total urinary arsenic and seafood consumption.
显示更多 [+] 显示较少 [-]Mercury (Hg) in fish consumed by the local population of the Jaguaribe River lower basin, Northeast Brazil
2014
Costa, B. G. B. | Lacerda, L. D.
The knowledge of Hg concentrations in fish is of considerable interest since these organisms are a major source of protein to coastal human populations and fishing communities. The main source of human exposure to Hg contamination occurs through the consumption of fish. In this paper, we compare Hg concentration in 13 fish species from Jaguaribe River lower basin and an adjacent coastal region in the northeastern coast of Brazil. We sampled fish from three stretches of the river: fluvial, estuarine, and marine regions. We tested the hypothesis that Hg concentration in muscle tissue vary according to species, location, and trophic level. Significant differences were observed among species and trophic level, but these could not be observed among the regions studied. As expected, the highest concentrations were observed in carnivorous fish (5.6–107.5; 26.9 ± 18.8 ng g⁻¹). Hg concentrations observed in this study are similar to those observed in regions of low environmental contamination. We estimated Hg intake to vary between 0.02 and 0.22 ng Hg kg body weight⁻¹ week⁻¹, for the average body weight of 56.7 kg, which was considered as low exposure and therefore, a low risk to consumers of fish from the regions studied.
显示更多 [+] 显示较少 [-]Mercury contamination in alligators (Melanosuchus niger) from Mamirauá Reservoir (Brazilian Amazon) and human health risk assessment
2014
Correia, Jozélia | Cesar, Ricardo | Marsico, Eliane | Diniz, George Tadeu Nunes | Camargo, Mauricio (Camargo-Zorro) | Castilhos, Zuleica
Mercury (Hg) concentrations in muscles of wild alligators (Melanosuchus niger) from the Mamirauá Reservoir (a reference area in the Brazilian Amazon) and the human health risks associated with its consumption were assessed. The mean Hg concentration in alligator muscles was 0.407 ± 0.114 μg/g (N = 61). Close to 5 % of the muscle samples showed Hg levels above the World Health Organization guideline for fish consumption (0.5 μg/g). A positive and significant relationship was observed between Hg concentrations in muscle and the age of the specimens. The dose-response approach suggests that close to 27.4 years is required for half of the exposed specimens to attain 0.5 μg/g. The hazard quotient (HQ) is a risk indicator which defines the ratio of exposure level and a toxicological reference dose. HQ resulted above the unity for all the specimens when the ingestion rate for riverine communities (200 g of muscle per day) is considered, indicating the existence of hazard. When the ingestion rate for market consumers (28.57 g/day) is considered, the risks are much lower (mean HQ = 0.55), suggesting that such group is not at risk. The establishment of local and regional ingestion rates for riverine populations and market consumers is extremely recommended.
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