The present work investigates nitrate and phosphate removal from synthetic treated slaughterhouse wastewater in a novel open raceway pond with sedimentation zone. For this purpose, microalgae Chlorella salina has been cultivated in synthetic wastewater and sedimentation zone has been added to enhance both algae separation in the system and nutrient removal. The effectiveness of Chlorella salina to treat nitrate and phosphate has been tested in open raceway ponds with harvest system. It has been found that Biomass concentration of the Chlorella salina is 1.35 g/L during 11 days of experiment. Also, maximum specific growth rate of the species in the pond has been 0.74 day-1. Throughout the cultivation period, nitrate and phosphate have been analyzed to show that their average removal efficiencies were 100% and 45%, respectively. It can be concluded that the growth of Chlorella salina in novel open pond system is an effective way to reduce nitrate and phosphate levels in slaughterhouse synthetic wastewater. Also, wastewater is suitable for algal growth.