Today, the development of agricultural industries, especially small and efficient agricultural sector has been paid more attention. The development of rural industries in the country led to job creation and absorption of surplus labor force in agriculture and also resulted in more exports and foreign exchange. This paper evaluates development indicators of process industries and accesses to regional inequalities in the cities of Isfahan province. The research method is descriptive-analytical. This paper tries to examine the process industries associated with agriculture in Isfahan province. Therefore, statistical data was collected and processed by SPSS and Arc View. The status of Isfahan process industries was analyzed using PIDI (Process industry development index) in order to grade the city industries conditions so that we can propose more desirable planning for optimal process industries and the processing of agricultural products. The results show that the eastern cities of the province are disadvantaged in terms of this index and are considered as the first priority in order to develop appropriate measures. The second level includes western and southern cities that are the second priority for the development. Last level of development has been drawn linearly from North-West to South-East and the final priority is allocated to this level.