Tandem Reaction of Tertiary Enamides as a Synthetic Strategy to Construct the Fused N-Pentacyclic Skeleton of Erythrina Alkaloid Derivatives
2020
Yang, Hanlin | Li, Wenzhong | Xu, Xin-Ming | Wang, Zu-Li
An exquisite protocol to the synthesis of erythrina-related structural derivatives was developed, which is composed of a nucleophilic addition of tertiary enamides to ketonic carbonyls and the trapping of acyliminium by an aromatic unit. This protocol afforded a powerful method for the construction of diverse fused N-pentacyclic skeletons in high efficiency and excellent diastereoselectivity by just using different acid catalysts.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
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