A practical one-pot procedure for the synthesis of N–H isoquinolones
2013
Lu, Shaonan | Lin, Yingfu | Zhong, Hongban | Zhao, Kang | Huang, Jianhui
A practical one-pot procedure for the preparation of N–H isoquinolones has been developed. This 2-step process via C–H activation of N-alkoxyl benzamides and NaH-mediated dealkoxylation reaction has been demonstrated to be a high yielding alternative methodology for the efficient synthesis of a wide range of representative N–H isoquiolones. In addition, the experimental precedent supported mechanism of the dealkoxylation reaction was also proposed.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
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