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New aspidosperma-type alkaloids from Tabernaemontana bovina

2022

Zhao, Xue | Du, Si-Yu | Liu, Jie | Liu, Jia-Ning | Jiang, Cheng-Shi | Zhu, Kong-Kai | Fang, Lei

Two new aspidosperma-type alkaloids, taberibogines C and D (1 and 2), along with three known ones (3–5), were isolated from the leaves of Tabernaemontana bovina. Their structures including absolute configurations were elucidated by extensive spectroscopic analysis and X-ray crystal diffraction. Alkaloids 1-2 exhibited moderate inhibitory effects on LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages.

AGROVOC Keywords

alkaloids macrophages nitric oxide spectral analysis tabernaemontana

Bibliographic information

Published in

Phytochemistry letters

Volume 49 Pagination 105 - 108 ISSN 1874-3900

Publisher

Entomological Society of America

Other Subjects

X-radiation; Aspidosperma-type; Anti-inflammatory activity; Tabernaemontana bovina; Plant biochemistry

Language

English

Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

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This bibliographic record has been provided by National Agricultural Library

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Links

DOI DOI https://dx.doi.org/10.1016/j.phytol.2022.03.016

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