Polyoxygenated cyclohexene derivatives from Monanthotaxis congoensis

Starks, Courtney M.; Williams, Russell B.; Rice, Stephanie M.; Norman, Vanessa L.; Lawrence, Julie A.; Goering, Matt G.; O’Neil-Johnson, Mark; Hu, Jin-Feng; Eldridge, Gary R.

Polyoxygenated cyclohexene derivatives from Monanthotaxis congoensis

2012

A phytochemical investigation of Monanthotaxis congoensis afforded eight polyoxygenated cyclohexenes as well as the known crotepoxide. Structures were determined using NMR, MS, and optical rotation analyses. One compound displayed moderate antiproliferative activity against NCI-H460 and M14 cancer cells.

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AGROVOC Keywords

annonaceae antineoplastic agents chemistry drug therapy epoxy compounds humans neoplasms neoplasms nuclear magnetic resonance spectroscopy pharmacology plant extracts

Bibliographic information

Published in

Phytochemistry

Volume 74 Pagination 185 - 189 ISSN 0031-9422

Publisher

Elsevier Ltd

Other Subjects

Drug effects; Phytogenic; Cyclohexenes; Cell line; Tumor; Cell proliferation; Monanthotaxis; Cyclohexenes; Therapeutic use; Molecular structure; Isolation purification

Language

English

License

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Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

Data Provider

This bibliographic record has been provided by National Agricultural Library

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Links

DOI http://dx.doi.org/10.1016/j.phytochem.2011.10.014

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