Synthesis of 3-fluoroalkenyl-3-trifluoromethyl-2-oxindoles by the reaction of indoline-2,3-diones with difluoromethylene phosphabetaine
2016
Liu, Yingle | Zhang, Ke | Huang, Yangen | Pan, Shen | Liu, Xiao-Qiang | Yang, Yi | Jiang, Yan | Xu, Xiu-Hua
An unprecedent reaction of indoline-2,3-diones and (triphenylphosphonio)difluoroacetate (PDFA) afforded novel 3-fluoroalkenyl-3-trifluoromethyl-2-oxindoles in moderate to excellent yields. These products could be transformed into other trifluoromethylated oxindole derivatives.
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