Palladium catalyzed addition of arylboronic acid or indole to nitriles: synthesis of aryl ketones
2014
Das, Tuluma | Chakraborty, Amarnath | Sarkar, Amitabha
Aryl ketones can be synthesized conveniently by a palladium catalyzed addition of arylboronic acid to nitriles in aqueous triflic acid. This catalytic system was extended to the addition of unprotected indoles to nitriles under a slightly modified condition to produce 3-acyl indoles in good yields.
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