Biodegradable polymer network encapsulated polyplex for DNA delivery
2013
Petrov, Petar D. | Ivanova, Nadya I. | Apostolova, Margarita D. | Tsvetanov, Christo B.
A novel gene delivery system is made by encapsulation of a polyplex between pDNA and cationic micelles with a biodegradable crosslinked shell. The outer shell can provide additional functionality to the system and protect DNA from degradation. The encapsulated polyplex exhibits a similar transfection efficiency compared to the naked polyplex.
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