Systems Biology in ELIXIR : Modelling in the spotlight
2022
Martins dos Santos, Vitor | Hancock, John M. | Anton, Mihail | Szomolay, Barbara | Ostaszewski, Marek | Arts, Ilja | Benfeitas, Rui | Dominguez Del Angel, Victoria | Ferk, Polonca | Fey, Dirk | Goble, Carole | Golebiewski, Martin | Gruden, Kristina | Heil, Katharina F. | Hermjakob, Henning | Kahlem, Pascal | Klapa, Maria I. | Koehorst, Jasper | Kolodkin, Alexey | Kutmon, Martina | Leskošek, Brane | Moretti, Sébastien | Müller, Wolfgang | Pagni, Marco | Rezen, Tadeja | Rocha, Miguel | Rozman, Damjana | Šafránek, David | Sheriff, Rahuman S.M. | Suarez Diez, Maria | Van Steen, Kristel | Westerhoff, Hans V. | Wittig, Ulrike | Wolstencroft, Katherine | Zupanic, Anze | Evelo, Chris T.
In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community believes that the infrastructure aspects of systems biology - databases, (modelling) tools and standards development, as well as training and access to cloud infrastructure - are not only appropriate components of the ELIXIR infrastructure, but will prove key components of ELIXIR's future support of advanced biological applications and personalised medicine. By way of a series of meetings, the Community identified seven key areas for its future activities, reflecting both future needs and previous and current activities within ELIXIR Platforms and Communities. These are: overcoming barriers to the wider uptake of systems biology; linking new and existing data to systems biology models; interoperability of systems biology resources; further development and embedding of systems medicine; provisioning of modelling as a service; building and coordinating capacity building and training resources; and supporting industrial embedding of systems biology. A set of objectives for the Community has been identified under four main headline areas: Standardisation and Interoperability, Technology, Capacity Building and Training, and Industrial Embedding. These are grouped into short-term (3-year), mid-term (6-year) and long-term (10-year) objectives.
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