Systems Biology in ELIXIR : Modelling in the spotlight

Martins dos Santos, Vitor; Hancock, John M.; Anton, Mihail; Szomolay, Barbara; Ostaszewski, Marek; Arts, Ilja; Benfeitas, Rui; Dominguez Del Angel, Victoria; Ferk, Polonca; Fey, Dirk; Goble, Carole; Golebiewski, Martin; Gruden, Kristina; Heil, Katharina F.; Hermjakob, Henning; Kahlem, Pascal; Klapa, Maria I.; Koehorst, Jasper; Kolodkin, Alexey; Kutmon, Martina; Leskošek, Brane; Moretti, Sébastien; Müller, Wolfgang; Pagni, Marco; Rezen, Tadeja; Rocha, Miguel; Rozman, Damjana; Šafránek, David; Sheriff, Rahuman S.M.; Suarez Diez, Maria; Van Steen, Kristel; Westerhoff, Hans V.; Wittig, Ulrike; Wolstencroft, Katherine; Zupanic, Anze; Evelo, Chris T.

Systems Biology in ELIXIR : Modelling in the spotlight

2022

In this white paper, we describe the founding of a new ELIXIR Community - the Systems Biology Community - and its proposed future contributions to both ELIXIR and the broader community of systems biologists in Europe and worldwide. The Community believes that the infrastructure aspects of systems biology - databases, (modelling) tools and standards development, as well as training and access to cloud infrastructure - are not only appropriate components of the ELIXIR infrastructure, but will prove key components of ELIXIR's future support of advanced biological applications and personalised medicine. By way of a series of meetings, the Community identified seven key areas for its future activities, reflecting both future needs and previous and current activities within ELIXIR Platforms and Communities. These are: overcoming barriers to the wider uptake of systems biology; linking new and existing data to systems biology models; interoperability of systems biology resources; further development and embedding of systems medicine; provisioning of modelling as a service; building and coordinating capacity building and training resources; and supporting industrial embedding of systems biology. A set of objectives for the Community has been identified under four main headline areas: Standardisation and Interoperability, Technology, Capacity Building and Training, and Industrial Embedding. These are grouped into short-term (3-year), mid-term (6-year) and long-term (10-year) objectives.

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