Functional genomics of HMGN3a and SMARCAL1 in early mammalian embryogenesis

Rodríguez Osorio, Nélida; Uzun, Alper; Kaya, Abdullah; Wang, Hongfeng; Parrish, John J.; Ilyin, Valentin A.; Memili, Erdogan; CENTAURO

Functional genomics of HMGN3a and SMARCAL1 in early mammalian embryogenesis

2009

ABSTRACT: Background: Embryonic genome activation (EGA) is a critical event for the preimplantation embryo, which is manifested by changes in chromatin structure, transcriptional machinery, expression of embryonic genes, and degradation of maternal transcripts. The objectives of this study were to determine transcript abundance of HMGN3a and SMARCAL1 in mature bovine oocytes and early bovine embryos, to perform comparative functional genomics analysis of these genes across mammals.

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COL0001262

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AGROVOC Keywords

blastocisto blastocyst cattle desarrollo embrionario embryonic development filogenia gene expression regulation genomics genómica models oocitos oocytes phylogeny

Bibliographic information

Publisher

BMC, Londres, Inglaterra

Other Subjects

Regulación del desarrollo de la expresión génica; Hmgn proteins; Dna helicases; Adn helicasas; Amino acid sequence; Modelos moleculares; Molecular; Developmental; Chromatin assembly and disassembly; Secuencia de aminoácidos; Proteínas hmgn; Bovinos; Ensamble y desensamble de cromatina

Language

English

Format

7, application/pdf, application/pdf

License

https://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/licenses/by-nc-sa/2.5/co/, info:eu-repo/semantics/openAccess, http://purl.org/coar/access_right/c_abf2

ISSN

1471-2164

Type

Artículo De Investigación; Http://purl.org/coar/resource_type/c_2df8fbb1; Https://purl.org/redcol/resource_type/art; Http://purl.org/coar/version/c_970fb48d4fbd8a85; Info:eu-Repo/semantics/article; Info:eu-Repo/semantics/publishedversion

In AGRIS since: 2024-10-18

Modification date: 2025-05-22

Format: Dublin Core

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Links

DOI DOI https://hdl.handle.net/10495/33392

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