Effects of the storage at 4 C degree and -20 C degree of vaccines against pox avium, newcastle disease and infectious laryngotracheitis in birds on their immunogenicity
2000
Dzhambazova, N. (Institut za Kontrol na Veterinarni Preparati, Sofia (Bulgaria)) | Popova, T.
The changes in titre and immunogenicity were studied of lyophilized vaccines stored in a refrigerator at 4 degree C and -20 degree C. It is demonstrated that the preservation of the biological properties depends on the duration of the storage. When appropriate storage is applied the vaccines maintain their efficiency for a longer period than the expire date determined by the producer. Vaccines are best preserved at -20 degree C for a period of 3 years.
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