HIV-1 protease inhibitory substances from the rhizomes of Boesenbergia pandurata Holtt.

Supinya Tewtrakul; Sanan Subhadhirasakul; Jindaporn Puripattanavong; Tassanee Panphadung

HIV-1 protease inhibitory substances from the rhizomes of Boesenbergia pandurata Holtt.

2003

Supinya Tewtrakul | Sanan Subhadhirasakul | Jindaporn Puripattanavong | Tassanee Panphadung

Four flavonoids (pinostrobin, pinocembrin, cardamonin and alpinetin) isolated from the ethanol extract of Boesenbergia pandurata Holtt. (yellow rhizome) were tested for their activities against HIV-1 protease (HIV-PR). The result showed that cardamonin exhibited an appreciable anti-HIV-1 PR activity with an IC50 value of 31 micro g/ml.

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AGROVOC Keywords

drug plants flavonoids human immunodeficiency virus inhibition proteinase inhibitors zingiberaceae

Bibliographic information

Published in

Songklanakarin Journal of Science and Technology (Thailand) | Warasan Songkhla Nakharin

Volume 25 Issue 4 ISSN 0125-3395

Pagination

pp. 503-508

Language

English

Note

Summaries (En, Th)

1 ill., 1 table

Translated Title

San tan enzyme HIV-1 protease chak ngao-krachai (Boesenbergia pandurata Holtt.)

Translated Title

San tan enzyme HIV-1 protease chak ngao-krachai (Boesenbergia pandurata Holtt.)

Type

Summary; Non-Conventional

In AGRIS since: 2005-05-15

Format: AGRIS AP

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HIV-1 protease inhibitory substances from the rhizomes of Boesenbergia pandurata Holtt.

2003

AGROVOC Keywords

Bibliographic information