HIV-1 protease inhibitory substances from the rhizomes of Boesenbergia pandurata Holtt.
2003
Supinya Tewtrakul | Sanan Subhadhirasakul | Jindaporn Puripattanavong | Tassanee Panphadung
Four flavonoids (pinostrobin, pinocembrin, cardamonin and alpinetin) isolated from the ethanol extract of Boesenbergia pandurata Holtt. (yellow rhizome) were tested for their activities against HIV-1 protease (HIV-PR). The result showed that cardamonin exhibited an appreciable anti-HIV-1 PR activity with an IC50 value of 31 micro g/ml.
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Эту запись предоставил Kasetsart University