Standardization Of Measles, Rubella, Polio ,T1, T2' and T3 Polyvalent Serum According To International Unit (IU)
2000
Shafyi ,Abbas
Bulk material consisted of a pool of Human sera prepared in departement of human viral vaccines at RAZI institute. The bulk material passed through 0,22 WM. Millipore filtration,. and distributed in a volume of 0.5ML in glass ampoules. freez - dried and stored AT - 20t: .No bacterial contamination was detected in the freez - dried material,. The product was also negative for HBS AG and HW Antibodies but not tested for hepatitis C virus. So the preparation should be Regaded as potentialy hazardous to health,. It should be used and discarded according to laboratory's safety procedures. The 11 Home prerared material 11 calibrated with the who standard material at the same time and conditions according to the instruction of NJ.B.S.C (national institute for blologial and standard - WHO). The intemational unit (l. U) of the effective constituent of the 11 Home made refrence antisera found to be as fallow: ANT M EASLES ANTIBODY 10 IU ANT RUBELLA ANTIBODY 320 IU ANT POLIO TYPEl ANTIBODY 6.25 IU ANT POLIO TYPE2 ANTIBODY 21.50 IU ANT POLIO TYPE3 ANTIBODY 3.20 IU
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