The inhibition of some cancers and the promotion of others by folic acid, vitamin B12, and their antagonists.

Herbert V.

The inhibition of some cancers and the promotion of others by folic acid, vitamin B12, and their antagonists.

1983

Herbert V.

A technical review suggests the hypothesis that folate or vitamin B12 deficiency (or any other cause of failure to methylate DNA and/or RNA) can activate malignancy by hypomethylation of oncogenes, and that the methylating oncogenes can inhibit malignancy by making them dormant. Specific attention is given to: the effects of folate deficiency; the role of vitamin B12; and studies on suppression testing to measure folate and vitamin B12 deficiencies in terms of slowing DNA synthesis.(wz).

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AGROVOC Keywords

acide folique acido folico antagonism antagonisme antagonismo carcinoma carcinome folic acid vitamin b12 vitamina b12 vitamine b12

Bibliographic information

Published in

Bristol Myers nutrition symposia

Volume 2

Pagination

v.273-287

Language

English

Note

92 ref. Paper presented at 2nd Annual Bristol Myers Symposium "Nutritional Factors in the Induction and Maintenance of Malignancy," Dec 9-10, 1982, Washington, D.C.

Type

Journal Article; Journal Part

Source

Bristol-Myers-nutrition-symposia (USA). (1983). v. 2 p. 273-287.

Corporate Author

National Diabetes Information Clearinghouse (USA). National Institute of Arthritis, Diabetes and Digestive and Kidney Diseases (USA).

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The inhibition of some cancers and the promotion of others by folic acid, vitamin B12, and their antagonists.

1983

AGROVOC Keywords

Bibliographic information