Compositions of polyphenols in wild chive, meadow salsify, garden sorrel and ag yoncha and their anti-proliferative effect
2012
Moravcikova, D., Univerzita Tomase Bati, Zlin (Czech Republic). Institut Zdravotnickych Studii | Kucekova, Z., Univerzita Tomase Bati, Zlin (Czech Republic). Centrum Polymernich Systemu | Mlcek, J., Univerzita Tomase Bati, Zlin (Czech Republic). Ustav Technologie a Mikrobiologie Potravin | Rop, O., Univerzita Tomase Bati, Zlin (Czech Republic). Ustav Technologie a Mikrobiologie Potravin | Humpolicek, P., Univerzita Tomase Bati, Zlin (Czech Republic). Centrum Polymernich Systemu
The aim of our study was to investigate the concentration of polyphenols in edible flowers of Allium schoenoprasum, Rumex acetosa, Trapogon pratensis and Trifolium repens, and their effect on proliferation activity of human hepatocellular carcinoma cells. The anti-proliferative effect was evaluated in vitro using the following concentrations of polyphenols: 100, 75, 50 and 25 microg/mL. Phenolic composition was determined by HPLC. Our results indicate that even low concentrations of polyphenols significantly inhibited cell proliferation. This effect was observed with all studied extracts and was independent on the composition of individual polyphenols.
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