Experimental sialodacryoadenitis virus infection in severe combined immunodeficient mice

Percy, D.H.; Williams, K.L.; Croy, B.A.

Experimental sialodacryoadenitis virus infection in severe combined immunodeficient mice

1991

Percy, D.H. | Williams, K.L. | Croy, B.A.

Mice with a severe combined immunodeficiency in B and T lymphocytes and natural killer cells (SCID-beige) were inoculated intranasally with sialodacryoadenitis (SDA) virus, a coronavirus of rats. Animals were killed at designated intervals and tissues were examined for evidence of viral infection by light microscopy and immunofluorescence microscopy. Based on these criteria, there was no evidence that these immundeficient mice were susceptible to infection with SDA virus.

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AGROVOC Keywords

animals animals crossbreds etiology immunology immunosuppression mice mice species differences

Bibliographic information

Published in

Canadian journal of veterinary research

Volume 55 Issue 1 Pagination 89 - 90 ISSN 0830-9000

Publisher

Springer Berlin Heidelberg

Other Subjects

Coronaviridae infections; Female; Laboratory; Immunosuppression (physiological); Rat coronavirus; Veterinary; Complications; Biological resistance; Rodent diseases; Immunologic deficiency syndromes; Disease susceptibility; Interspecific variation

Language

English

Note

Summary in french.

2019-12-04

Type

Text; Journal Article

In AGRIS since: 2024-02-27

Format: MODS

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Experimental sialodacryoadenitis virus infection in severe combined immunodeficient mice

1991

AGROVOC Keywords

Bibliographic information