Experimental sialodacryoadenitis virus infection in severe combined immunodeficient mice

Percy, D.H.; Williams, K.L.; Croy, B.A.

Experimental sialodacryoadenitis virus infection in severe combined immunodeficient mice

1991

Percy, D.H. | Williams, K.L. | Croy, B.A.

Mice with a severe combined immunodeficiency in B and T lymphocytes and natural killer cells (SCID-beige) were inoculated intranasally with sialodacryoadenitis (SDA) virus, a coronavirus of rats. Animals were killed at designated intervals and tissues were examined for evidence of viral infection by light microscopy and immunofluorescence microscopy. Based on these criteria, there was no evidence that these immundeficient mice were susceptible to infection with SDA virus.

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Mots clés AGROVOC

animals animals crossbreds etiology immunology immunosuppression mice mice species differences

Informations bibliographiques

Publié dans

Canadian journal of veterinary research

Volume 55 Numéro 1 Pagination 89 - 90 ISSN 0830-9000

Editeur

Springer Berlin Heidelberg

D'autres materias

Coronaviridae infections; Female; Laboratory; Immunosuppression (physiological); Rat coronavirus; Veterinary; Complications; Biological resistance; Rodent diseases; Immunologic deficiency syndromes; Disease susceptibility; Interspecific variation

Langue

anglais

Note

Summary in french.

2019-12-04

Type

Text; Journal Article

Sur AGRIS depuis: 2024-02-27

Format: MODS

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Experimental sialodacryoadenitis virus infection in severe combined immunodeficient mice

1991

Mots clés AGROVOC

Informations bibliographiques