Structure–activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain
2011
A series of 2,4-diphenyl-1H-imidazole analogs have been synthesized and displayed potent human CB2 agonist activity. Many of these analogs showed high functional selectivity over human CB1 receptors. The syntheses, structure–activity relationships, and selected pharmacokinetic data of these analogs are described.
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Bibliographic information
Publisher
American Association for the Advancement of Science
Other Subjects
Structure-activity relationships
Language
English
Type
Journal Article; Text
2024-02-28
2026-02-03
MODS
Data Provider
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