Structure–activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain
A series of 2,4-diphenyl-1H-imidazole analogs have been synthesized and displayed potent human CB2 agonist activity. Many of these analogs showed high functional selectivity over human CB1 receptors. The syntheses, structure–activity relationships, and selected pharmacokinetic data of these analogs are described.
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Библиографическая информация
Издатель
American Association for the Advancement of Science
Другие темы
Structure-activity relationships
Язык
Английский
Тип
Journal Article; Text
2024-02-28
2026-02-03
MODS
Поставщик данных
Эту запись предоставил National Agricultural Library
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