The relationship between short-term PM2.5 exposure and outpatient visits for acne vulgaris in Chongqing, China: a time-series study
2022
Li, Xiang | Zhou, Lai-Xin | Yang, Li-Li | Huang, Xiao-Long | Wang, Nan | Hu, Yue-Gu | Tang, En-Jie | Xiao, Hua | Zhou, Yu-Meng | Li, Ya-Fei | Lu, Yuan-Gang | Cai, Tong-Jian
Many researches have reported the air pollution impacts, either long term or short term, on inflammatory skin diseases, but there are few studies on the relation between PM₂.₅ and acne vulgaris. To determine the correlation between short-term PM₂.₅ exposure and acne outpatient visits, data for 120,842 acne vulgaris outpatient visits between December 2013 and December 2019 were obtained from three large hospitals in Chongqing, China. Both single-pollutant models and two-pollutant models were established to explore the relationship between PM₂.₅ exposure and acne outpatient visits. The stratified analyses were conducted through two-sample z-tests to investigate the possible gender (male or female) and age (< 25 years or ≥ 25 years) differences in PM₂.₅ effects. The results demonstrated positive correlations between PM₂.₅ concentrations and acne outpatient visits. A 10 μg/m³ increase in PM₂.₅ concentration was associated with a 1.71% (95% CI: 1.06–2.36%) increase in acne outpatient visits at lag 0–7 day. Stratified analyses showed that PM₂.₅ effects were greater in individuals aged ≥ 25 years than those aged < 25 years, but no gender difference was found. In conclusion, short-term PM₂.₅ exposure was positively associated with the risk of acne outpatient visits, especially for people ≥ 25 years old.
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