The relationship between short-term PM2.5 exposure and outpatient visits for acne vulgaris in Chongqing, China: a time-series study

Li, Xiang; Zhou, Lai-Xin; Yang, Li-Li; Huang, Xiao-Long; Wang, Nan; Hu, Yue-Gu; Tang, En-Jie; Xiao, Hua; Zhou, Yu-Meng; Li, Ya-Fei; Lu, Yuan-Gang; Cai, Tong-Jian

The relationship between short-term PM2.5 exposure and outpatient visits for acne vulgaris in Chongqing, China: a time-series study

2022

Many researches have reported the air pollution impacts, either long term or short term, on inflammatory skin diseases, but there are few studies on the relation between PM₂.₅ and acne vulgaris. To determine the correlation between short-term PM₂.₅ exposure and acne outpatient visits, data for 120,842 acne vulgaris outpatient visits between December 2013 and December 2019 were obtained from three large hospitals in Chongqing, China. Both single-pollutant models and two-pollutant models were established to explore the relationship between PM₂.₅ exposure and acne outpatient visits. The stratified analyses were conducted through two-sample z-tests to investigate the possible gender (male or female) and age (< 25 years or ≥ 25 years) differences in PM₂.₅ effects. The results demonstrated positive correlations between PM₂.₅ concentrations and acne outpatient visits. A 10 μg/m³ increase in PM₂.₅ concentration was associated with a 1.71% (95% CI: 1.06–2.36%) increase in acne outpatient visits at lag 0–7 day. Stratified analyses showed that PM₂.₅ effects were greater in individuals aged ≥ 25 years than those aged < 25 years, but no gender difference was found. In conclusion, short-term PM₂.₅ exposure was positively associated with the risk of acne outpatient visits, especially for people ≥ 25 years old.

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