Studies of the toxicity of Helminthosporium maydis

Ciegler, A.; Richard, J.L.; Ellis, J.J.; Cysewski, S.J.

Studies of the toxicity of Helminthosporium maydis

1972

Ciegler, A. | Richard, J.L. | Ellis, J.J. | Cysewski, S.J.

Isolates of Helminthosporium maydis from blighted corn were tested for toxicity in mice, rats, swine, rabbits, microorganisms, and tissue culture. Extracts of grains, mycelia, and culture supernatant fluids killed mice on intraperitoneal (ip) injection, but were nontoxic on administration by mouth to swine. The toxin was partially purified and appears to be a glycophospholipid. Histopathological examination revealed that the toxin acted as a severe irritant on ip injection, causing death in laboratory animals. In skin tests with rabbits, considerable exudation occurred, rather than necrosis.

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AGROVOC Keywords

administration animal feed animals biosynthesis bipolaris maydis chromatography chromatography cochliobolus heterostrophus culture media cystine feed contamination food contamination glycolipids histopathology methods mice mice mice microorganisms mycotoxins mycotoxins pathogenicity pharmacology phospholipids plant diseases plant extracts rabbits rabbits rats rats rats salmonella selenium skin tests swine swine toxicity toxicology zea mays

Bibliographic information

Published in

Applied microbiology

Volume 23 Issue 3 Pagination 586 - 591 ISSN 0003-6919

Other Subjects

Administration dosage; And immunology; Veterinary pharmacology; Corn; Oral; Growth development; Inbred strains; Injections; Intraperitoneal; Female; Mitosporic fungi; Thin layer; Male; Glycosopholipids; Inbred strains; Toxicity testing; Food microbiology; Isolation purification; Feed contamination and toxicology

Language

English

Note

Paper presented at the american society for microbiology meeting held may 2-7, 1971, minneapolis, minnesota.

Includes references.

2019-12-05

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Type

Text; Journal Article

In AGRIS since: 2024-02-28

Format: MODS

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Links

https://handle.nal.usda.gov/10113/30903

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