Studies of the toxicity of Helminthosporium maydis

Ciegler, A.; Richard, J.L.; Ellis, J.J.; Cysewski, S.J.

Studies of the toxicity of Helminthosporium maydis

1972

Ciegler, A. | Richard, J.L. | Ellis, J.J. | Cysewski, S.J.

Isolates of Helminthosporium maydis from blighted corn were tested for toxicity in mice, rats, swine, rabbits, microorganisms, and tissue culture. Extracts of grains, mycelia, and culture supernatant fluids killed mice on intraperitoneal (ip) injection, but were nontoxic on administration by mouth to swine. The toxin was partially purified and appears to be a glycophospholipid. Histopathological examination revealed that the toxin acted as a severe irritant on ip injection, causing death in laboratory animals. In skin tests with rabbits, considerable exudation occurred, rather than necrosis.

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Mots clés AGROVOC

administration animal feed animals biosynthesis bipolaris maydis chromatography chromatography cochliobolus heterostrophus culture media cystine feed contamination food contamination glycolipids histopathology methods mice mice mice microorganisms mycotoxins mycotoxins pathogenicity pharmacology phospholipids plant diseases plant extracts rabbits rabbits rats rats rats salmonella selenium skin tests swine swine toxicity toxicology zea mays

Informations bibliographiques

Publié dans

Applied microbiology

Volume 23 Numéro 3 Pagination 586 - 591 ISSN 0003-6919

D'autres materias

Toxicity testing; Administration dosage; Oral; Feed contamination and toxicology; Food microbiology; Intraperitoneal; Injections; Corn; Female; Isolation purification; Inbred strains; Veterinary pharmacology; And immunology; Male; Thin layer; Inbred strains; Glycosopholipids; Mitosporic fungi; Growth development

Langue

anglais

Note

Paper presented at the american society for microbiology meeting held may 2-7, 1971, minneapolis, minnesota.

Includes references.

2019-12-05

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Type

Journal Article; Text

Sur AGRIS depuis: 2024-02-28

Format: MODS

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Cette notice bibliographique a été fournie par National Agricultural Library

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https://handle.nal.usda.gov/10113/30903

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Studies of the toxicity of Helminthosporium maydis

1972

Mots clés AGROVOC

Informations bibliographiques