Treatment of hyperlipoproteinemia with type-specific' diets under metabolic ward conditions: effects on serum lipoproteins and serum lipid esters
1981
Boberg, J. | Gustafsson, I.B. | Karlstrom, B. | Lithell, H. | Vessby, B. | Werner, I.
Forty-five hyperlipoproteinemic patients were treated for 2 weeks with lipid-lowering diets using 7 different daily menus of identical composition at all energy levels. The fat and protein content of the diets provided 34-35% and 20% of the energy, respectively; the dietary polyunsaturated/saturated fatty acid ratios ranged from 1.3-2.0; the cholesterol content was 0.14 g per 6.7 MJ. Under these lipid-lowering isoenergetic dietary conditions, the patients showed decreases of 27-33% in very low density lipoprotein triglycerides, 16-19% in low density lipoprotein, and 5-13% in high density lipoprotein cholesterol, compared with patient levels observed during a preceding 2-week period on a control diet. Since no changes were observed in lipoprotein removal capacity, it was concluded that the observed effects were primarily due to a reduced production of serum lipoproteins. (wz)
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