In Vitro studies of fatty acid metabolism in vitamin B6 deficient rats

Dussault, Pierre E.; Lepage, Marius

In Vitro studies of fatty acid metabolism in vitamin B6 deficient rats

1979

Dussault, Pierre E. | Lepage, Marius

Extract: The oxidation of palmitate, linoleate, and arachidonate as well as their incorporation into lipids was investigated in vitamin B6 deficient rats using liver slices and isolated mitochondria. In experiments on fatty acid oxidation in liver slices, a decrease was observed in the production of 14CO2 from radioactive palmitate and linoleate, but not from arachidonate. Major changes occurred in metabolism of palmitate and linoleate. The decrease in the arachidonate content previously observed in rat tissues could not be explained by alteration in the metabolism of this fatty acid.

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AGROVOC Keywords

animals biosynthesis cholesterol fatty acids fatty acids lipid metabolism lipids liver metabolism oxidation phospholipids pyridoxine rats triglycerides vitamin deficiencies

Bibliographic information

Published in

Journal of nutrition

Volume 109 Issue 1 Pagination 138 - 141 ISSN 0022-3166

Other Subjects

In vitro techniques; Metabolic studies; Linoleic acids; Animal experimentation; Palmitic acids; Nonesterified; Arachidonic acids; Vitamin b 6 deficiency; Male

Language

English

Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

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In Vitro studies of fatty acid metabolism in vitamin B6 deficient rats

1979

AGROVOC Keywords

Bibliographic information