Sequence of an exon of the feline p53 gene-mutation in a lymphosarcoma

Mayr, B.; Heczko, U.; Schellander, K.; Schleger, W.; Reifinger, M.

Sequence of an exon of the feline p53 gene-mutation in a lymphosarcoma

1993

Mayr, B. | Heczko, U. | Schellander, K. | Schleger, W. | Reifinger, M.

Exon 8 of tumour suppressor gene p53 was sequenced in domestic cats and showed remarkable similarity to the human sequence. Only four of the 13 nucleotide differences gave rise to interspecific amino acid differences. In an investigated lymphosarcoma we detected a mutation cgg leads to tgg (arginine leads to tryptophan) in codon no. 282.

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AGROVOC Keywords

amino acid sequences amino acids animals cats cats codon exons genes genes genetics humans lymphoma lymphosarcoma mutation mutation pathology polymerase chain reaction

Bibliographic information

Published in

British veterinary journal

Volume 149 Issue 4 Pagination 387 - 390 ISSN 0007-1935

Other Subjects

Sequence homology; Amino acid; P53; Cat diseases; Amino acid sequence; Non-hodgkin; Base sequence; Nucleotide sequences; Veterinary; Molecular sequence data

Language

English

Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

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Sequence of an exon of the feline p53 gene-mutation in a lymphosarcoma

1993

AGROVOC Keywords

Bibliographic information