Sequence of an exon of the feline p53 gene-mutation in a lymphosarcoma
1993
Mayr, B. | Heczko, U. | Schellander, K. | Schleger, W. | Reifinger, M.
Exon 8 of tumour suppressor gene p53 was sequenced in domestic cats and showed remarkable similarity to the human sequence. Only four of the 13 nucleotide differences gave rise to interspecific amino acid differences. In an investigated lymphosarcoma we detected a mutation cgg leads to tgg (arginine leads to tryptophan) in codon no. 282.
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