In the conditions of the Republic of Belarus there was analyzed the efficiency of administration of nonconventional feed materials in diets of highly productive cows and its influence of indexes of natural resistance at different physiological stages of animals. In the process of studying of adaptation processes of highly productive cows at different stages of lactation it was determined that feeding with nonconventional melanoidin-humic additives at different physiological periods rendered a positive influence of highly productive cows, promoted the increasing of natural resistance of animals and improvement of immuno-humoral blood indexes. Administration of an additive Ehkolin in a ration of highly productive cows with stimulation for increasing milk flow in a dose of 100 ml per head promoted the increasing of blood serum bactericidal activity on 5,2%, beta-lysine activity - on 7,2%. Feeding of animals at a basic lactation period with 50 ml of preparation Ehkolin-2 provided the maximum increasing of lysozyme activity of blood serum (on 6,2%) and beta-lysine activity of blood serum (on 12,7%), and also promoted the activation of leukocytopoiesis. Addition of Ehkolin-3 in ration structure of dry cows in a dose of 750 ml increased the indexes of lysozyme activity of blood serum on 7-8,6%, bactericidal activity of blood serum - on 2,2-3,6% and beta-lysine activity of blood serum - on 2,2-3,6%.

In the conditions of the Republic of Belarus there were determined the doses of application of siliceous sapropel as well as there were studied the indexes of ruminal digestion and digestibility of diet nutrient substances by bull calves. The studied siliceous sapropel of the lake Pribylovichi (Belarus) occurence on 42% consisted of organic substances and on 58% - of mineral substances: calcium, phosphorus, magnesium, potassium, sodium, iron, zinc, manganese, and copper. The studied sample of sapropel did not render toxic action on test objects of infusorian Tetrahymena pyriformis in the conditions of its addition into the basic forage in number of 1%; 3%; 5%; and 10%. However, its higher concentrations (10%) retarded the development of Protozoa. Feed additives with the content of siliceous sapropel in mixed fodder in dose of 1%, 3% and 5% increased the relative biological value of forage in the experiments on test objects of infusorians Tetrahymena pyriformis in the average respectively on 5,4%, 5,0 and 2,6%. Higher concentrations of sapropel in mixed fodder (5 and 10%) lowered its nutritional value. Inclusion of siliceous sapropel in bull calve rations activated the enzymatic processes in farding bag and increased the digestibility nutritive elements on 2,3-3,6% except for protein, digestibility which was practically at identical level at animals of all groups.

In the conditions of the Republic of Belarus there was analyzed the efficiency of application of a whole milk substitute Biomilk-11 and feed additive SFDK-1 (biologically active enzymatic feed additive) for breeding of young stock of cattle, by an example of calves of black-and-white breed. In course of the study there was analyzed the composition of the feed additive SFDK-1 (weight fraction of dry matter; weight fraction of protein; content of amine nitrogen; cellulose fiber activity) as well as the physical and chemical indexes of the whole milk substitute Biomilk-11 (moistness; crude protein; crude fat; crude fibre). There were presented indexes of live weight gain of experimental and control calves as well as the dynamics of average daily weight gains in experimental group. Research results proved the efficiency of application of both additive for calves feeding.

Research on working out of a new fodder additive on the basis of rape (Brassica napus) phospholipids which included mineral substances necessary for normal functioning of cattle was realized in the conditions of the Republic of Belarus. Results of biochemical analysis of 35240 blood samples revealed that 15-40% of studied animals had abnormalties in vitamin, protein and mineral metabolism and lowering of immunobiological disease resistance. There was correlation dependence between the degree of metabolic orders and the state of forage reserve of a forage reserve. The lowering of forage reserve caused the increasing of metabolic disorders. As a whole forages of the surveyed farms were low in content of copper, zinc, cobalt and selenium and could not provide physiological requirements of animals without introduction into rations of specialized additives

Investigation of histological structures of liver of fattening broiler chickens after application of concentrate of E and F vitamins produced on the basis of rapeseed oil was realized in the conditions of the Republic of Belarus in order to evaluate their efficiency for prophylaxis of massive hepatic necrosis. Research results showed that application of the vitamins on the basis of rapeseed oil promoted the support of structural properties of hepatic cells that proved their higher antioxidant efficiency in comparison with synthetic vitamin analogues

Investigation of influence of probiotic Dialact and immunostimulant Alveozan on digesting of nutritive substances by broiler chickens of Kobb-500 cross, as well as control over their individual development were realized in the conditions of the Republic of Belarus. The first (control) group of chicken was given standard well-balanced ration. Chickens of the second group were administrated immunostimulant Alveozan in dose of 10 mkg/kg of live weight with drinking water once a day in course of 5 days, with 10 days interval till the end of the growing period. Chickens of the third group were administrated preparation Dialact in dose of 0,1-0,2 ml with drinking water once a day in course of 3 days, with 14 days interval till the end of growing period. Chickens of the fourth group were given Alveozan in dose of 10 microgram/kg of live weight once a day in course of 5 days with 10 days interval, and Dialact in dose 0,1-0,2 ml once a day in course of 3 days, with 6 and 14 days interval. Research results showed that complex application of probiotic Dialact and immunostimulant Alveozan increased the viability of chickens on 100%, average live weight - on 5,1%, average daily weight gain - on 5,1%. Administration of Dialact and Alveozan, both separately and in complex, increased the digestibility of nutritive substances of mixed fodders: application of nitrogen increased on 1,93-6,38%, application of calcium decreased on 10,41-12,54%, phosphorus use increased on 2,38%

Influence of monocalcium phosphate on natural resistance and clinical indexes of blood of breeding bull calves of white-and-black breed was realized in the conditions of the Republic of Belarus. Bull calves of the first (control) group in the composition of their main ration were fed with mixed fodder K-66-b, hay, green mass and as a balanced phosphoric-potassium additive they were fed with8 grams of defluorinated phosphate per 1 kg of mixed feed. Bulls of the second, third and fourth experimental groups in combination with the standard ration instead of difluoridated phosphate were fed with 5; 10; and 15 grams monocalcium phosphate per 1 kg of combined feed, respectively. Research results showed that application of fodder monocalcium phosphate in addition to the main ration made it possible to increase calcium and phosphorus content in blood of experimental bull calves. In the control group phosphorous content was 2,17 micromole, in the experimental groups – 2,40-2,78 micromole; calcium content – 2,50 and 2,58-2,88 micromole, respectively. The analyzed additive rendered positive effect on protein exchange, increased the natural resistance, bacterial growth-inhibitory activity in blood serum in the third, fourth and second groups on 50,3%, 42,5%, and 40,3%, respectively; lysozyme activity – on 46,0%, 39,2%, and 32,3%, respectively; phagocytic activity of leukocytes – on 21,9%, 25%, and 19,1%

For the determination of efficiency of a new produced in the Republic of Belarus preparation Ehkvikar there was modeled a test with a diaphoresis of guinea pigs by means of their staying in a thermostat at a temperature of 45-50 deg C in course of 30 minutes. Before and after the test there was taken a blood test for its analysis. Results of the experiment showed that together with sudo the animals lost 1-2 % of their body. There was stated the increasing of all blood corpuscles as well as lowering in 1,3-1,47 times of such elements as chlorine, sodium, potassium, and also T lymphocytes and bursa-derived lymphocytes. Application Ehkvikar promoted the stabilization of biochemical and morphological parameters of blood, and also the immune status of laboratory animals. Thus, Ehkvikar preparation promoted the compensation of losses of electrolytes with sudor of guinea pigs and in future can be studied by an example of horses for completion of electrolytes losses in the conditions of increased physical exercises.

In article results of studying of efficiency and quality of poultry-fanning production under influence chitosan are considered. It is established that the preparation promotes safety increase on 0,5%, efficiency on 6% and biological value of meat on 20% at chickens whom gave to drink chitosan in a dose of 5 mg/goal from 32 day age it) comparison with the control. Such technological reception leads to decrease the receipt in an organism of a chicken of microtoxins, heavy metals, products of a metabolism of bacteria

Results of researches on studying influence separate and combination feeding fermented compositions Fekord-2004C and biologically active additive Oxide Peat on energy of growth and protective properties of an organism of pigs – deprivation are stated. It is established that enrichment of mixed fodder investigated by the fodder fermented additive Fekord-2004C at the rate of 0,15 kg on ton of mixed fodder in combination application with biologically active substance Oxide Peat in a doze of 1,0 kg on ton of mixed fodder promotes increase of growth rate of pigs on development and to decrease of the charge of forages on unit of a gain of alive weight and safety of pigs