The spectrum of acaricides changes continuously and improves. At the same time, big attention is given to research of new, more effective preparations meeting modern requirements. Research on studying the efficiency of Akaribil preparation against swine sarcoptosis (Sarcoptidae) was realized in the conditions of swine breeding farm in the Republic of Belarus. The preparation possesses high insect-acaricidal activity. In the conditions of the preparation storage and repeated opening of a ware in the course of tests there were stated no changes in drug smell or color. The scheme of the preparation application is applied in industrial production technology. It possesses anti-inflammatory properties, antiseptic stimulating healing of skin damages, does not irritate integuments, renders weak irritating effect on mucous membranes of eyes. In recommended doses Akaribil does not cause any adverse effects and complicating disease. There were stated no contraindications to preparation application. High therapeutic efficiency against arachnoentomosis was proved. Application the preparation made it possible not only to reduce disease incidence and animal death, but also to facilitate the severity of scabietic diseases. As a result of realized research it was established that efficiency of Akaribil against swine sarcoptosis was 100%.

In the conditions of the Republic of Belarus there were studied the anthelminthic properties of preparative forms of elecampane (Inula helenium) (herbal infusion, tincture, liquid and dry extracts). Research results showed that the analyzed preparative forms in the administrated doses possesed high therapeutic efficiency against strongyloidosis and strongylatosis of gastroenteric path of sheep. Thus, according to results of research it was established, that the highest therapeutic effect rendered herbal infusion of elecampane in a dose of 6 ml/kg live weight once a day three days continuously; and the antiparasitic efficiency was 60%. Application of elecampane tincture in a dose of 1 ml/kg live weight once and 0,5 ml/kg of live weight twice rendered the 100% therapeutic effect. Administration of a liquid extract of elecampane in a dose of 0,2 ml/kg live of weight once and 0,1 ml/kg of live weight twice rendered 100% therapeutic effect. Application of elecampane dry extract in a dose of 30 mg/kg of live weight once and 25 mg/kg of live weight twice rendered 100% therapeutic effect.

In the conditions of the Republic of Belarus there were studied circadian rhythms of some haemotological and biochemical blood indexes of clinically healthy calves and calves with a respiratory syndrome. There was analyzed the efficiency of administration a new complex mineral preparation CMP for correction of internal desynchronoses in complex therapy of calves with respiratory pathologies. Diseases of calves with a respiratory syndrome were accompanied by infringements of circadian fluctuations rhythm (internal desynchronosis) of haemotological and biochemical blood indexes. Application of an antimicrobial preparation Ampicillin for treatment of respiratory diseases of calves promoted the recovery of calves. Introduction of CМP preparation into therapeutic regimen of calves with respiratory syndrome proved to be rather effective; it promoted the correction of metabolic desynchronoses which accompanied the basic disease. Combined application of CМP and Ampicillin made it possible to speed up the clinical recovery of calves and on 30% to prevent animal mortality.

Investigation of method of gastroenteritis treatment of stores by means of application of enterosorbents was realized in the conditions of the Republic of Belarus. For the experiment there was used preparation Lactofiltrum containing 80% of hydrolyzed lignin and 20% of lactulose applied in dose of 0,3 g/kg once a day during 7 days. Efficiency of application of Lactofiltrum was compared with enterosorbent SV-2, which contained alcaline hydrolyzed lignin applied in dose of 1 g/kg once a day during 7 days. Four experimental groups piglets sick with gastroenteritis in the age of 1,5-2 months, with body weight of 15-17 kg were used in the experiment. The first group piglets were entered 0,3 g/kg body mass of Lactofiltrum once a day during 7 days. The second group piglets were entered enterosorbent SV-2 in dose of 1 g/kg in course of 7 days. For the piglets of the third group there was applied the complex of analysed preparations in same course of treatment. The fourth group of piglets was entered enrotim 10% in dose of 1 ml/ 20 kg of body mass. All animals had the same conditions of feeding and keeping. Research results showed that application of Lactofiltrum, SV-2 and their complex provided high antioxidative, detoxification, gepathoprotective activities. These preparations proved to be effective means of pathogenetic therapy for the treatment of gastroenteritis of piglets, both as individual preparations, and complex application. Comparative estimation of treatment methods of gastroenteritis showed that these preparations (except enrotim 10%) made it possible to regulate the metabolic processes due to elimination of intoxication, positive influence on hematopoiesis. The preparations lowered the duration of clinic manifestation of a disease and facilitated its duration, had gepathoprotective and antioxidative activity

Study of sensitivity of Paenibacillus alvei to different antibiotic preparations (penicillin, tetracycline, neomycine, kanamycin, ampicillin, polymyxin, laevomycetin, enrofloxacin, tylosin, and streptomycin) was realized in the conditions of the Republic of Belarus. As the material of the research there was used the culture of agent the European foul brood caused by Paenibacillus alvei. Determination of therapeutic effectiveness of antibacterial agents in vitro conditions made it possible to choose the appropriate preparation for its use at beeyards with European foul brood caused by Paenibacillus alvei. During the experimental work there were used 10 antibacterial disks with various antibiotics. The best result against Paenibacillus alvei was shown by Tilozin, the diameter zone of growth inhibition was about 47,2+/-3,43 mm.

Sensitivity of European Faulbrut causative agent to Gentavet preparation was studied in the conditions liquid nutritive media in vitro in the Republic of Belarus. Research results showed that the studied preparation rendered the poisonous influence on European Faulbrut causative agent in concentration of 0,3 mkg/ml with the maximum rate 1:131072. The antibiotic showed the bacteriostatic ability in concentration of 0,15 mkg/ml. The antibacterial preparation did not influence the European Faulbrut causative agent in concentration of 0,01 mkg/ml. The total bacteriostatic effect the drug showed in concentration of 0,22 mkg/ml and its dilution of 1:196608.

A description of a method of chemical inactivation of Aujeszky's disease virus by teotropin was studied in the conditions of the Republic of Belarus. The developed inactivated viral suspension was tested for its antigenic activity. On the basis of realized experiments there were determined the optimal parameters of inactivation of Aujeszky's disease virus y means of 0,1% solution of teotropin under temperature of 37 deg C, pH 7,8 and duration of exposition of 24 hours. There were studied indexes of antigenic activity of inactivated virus

Analysis of synchronization of oestrus of cows by means of Ovsynch and Pre-Synch methods was realized in the conditions of the Republic of Belarus. Research results showed that estrus synchronization by means of Pre-Synch method proved to be more efficient by means of higher percentage of fertilization after the first and second insemination in comparison with Ovsynch method. Treatment of cows with the substances Surfagon and Tetravit for synchronization of oestrus did not render negative effect on milk quality and safety.

Results of studying the efficiency of iodine containing preparation Jodon which was applied to highly productive cows with hypovarianism and to servicing bulls in order to increase their reproductive function realized in the Republic of Belarus were presented. On the basis of realized studies there was proved the considerable efficiency of Jodon preparation.

Development of a new national preparation for the preventive maintenance of cow mastitis, fissures of milking tubes skin of cow udder was realized in the conditions of the Republic of Belarus. The preparation Maz' Solnechnaya ("Unguent Solnechnaya") did not contain antibiotics, hormones and other synthetic components. Natural components of a preparation provide long anti-inflammatory action, stimulate local blood circulation, regeneration of epidermis and accelerate processes of healing of microtraumas. Besides it possesses high efficiency at preventive maintenance of mastitises at cows.