The thyroid glands of male rats treated with oestrogen during various stages of development
1988
Sekulic, M. | Pantic, V. (Institute for Biological Research "Sinisa Stankovic", Beograd (Yugoslavia))
Thyroid glands of male rats treated with estradiol dipropionate during the neonatal (3rd day), juvenile (16th day) or peripubertal (38th day) period of life were investigated. The following was established: the height of follicular epithelium was significantly reduced in all animals neonatally treated with estradiol; a significant decrease of follicular cell height was also evident in adult animals treated with estradiol during the juvenile period; in all experimental groups the follicular cell volume density was significantly reduced while the colloid volume was increased resulting in a diminution of the activation indices; the cysternoid GER and significantly less developed Golgi complexes were more prominent in follicular cells of animals treated during neonatal period than during later periods of development.
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