Oxytocin and vasopressin, like LH [LH-like hormones] sttimulate cyclic APM production by porcine ovarian granulosa cells
1996
Sirotkin, A.V. | Bulla, J. | Kubek, A.
To understand the intracellular mechanisms of non-apeptide hormone action within ovaries, the influence of oxytocin and vasopressin on cAMP release by porcine granulosa cells was studied. It was observed that addition of arginine-8-vasopressin or oxytocin stimulated cAMP output from cultured granulosa cells. Moreover, vasopressin, but not oxytocin, increased LH-stimulated cAMP release. It is proposed that vasopressin and oxytocin, like LH, can exert their action on the porcine ovary via the activation of cAMP-dependent intracellular mechanisms
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