Absence of the severe combined immunodeficiency disease gene among Arabian horses in Poland
1999
Terry, R.R. | Cothran, E.G. (Kentucky University, Lexington, (USA). Dep. of Veterinary Science) | Cholewinski, G. ( Agricultural University, Poznan (Poland). Lab. of Horse Genetic Markers)
Severe combined immunodeficiency disease is an autosomal recessive disease occurring in Arabian horses. A recent discovery of a five base pair deletion in the gene encoding DNA-PK catalytic subunit has led to a PCR based test to screen for carriers of this disease. It has been suggested that the origin of this mutation arose from a stallion that originated in Poland. For this reason the occurrence of the SCID allele was tested on a representative sample of Polish horses
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