Comparison of Micronulcleus Induction of Cigarette Smoke Condensate in Various Cell Lines
2003
Shin, H.J. | Sohn, H.O. | Lee, Y.G. | Lee, D.W. | Hyun, H.C. (KT G Central Research Institute, Daejeon, Republic of Korea)
Although tobacco smoke has been known to have genotoxicity as well as cytotoxicity, the sensitivity of the cell lines used against cigarette smoke is poorly understood. The objective of this study was to evaluate and compare the genotoxicity of several cell lines, which are routinely used in the in vitro assays, with cigarette smoke condensate(CSC) of Kentucky Reference Cigarette 1R4F.
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