Comparing the Performance of One-column Process and Four-zone Simulated Moving Bed by Computer Simulation
Kim, Y.S.;Lee, C.H.;Koo, Y.M.(Inha University, Incheon, Republic of Korea)E-mail:ymkoo@inha.ac.kr | Wankat, Phillip C.(Purdue University, West Lafayette, IN, USA)
A new one-column chromatography process, analogous to a four-zone simulated moving bed (SMB), was presented. The basic principle of the process was identical to that of a four-zone SMB. The process consisted of one chromatographic column and four tanks, instead of the four columns in the four-zone SMB (1-1-1-1), and has been used for the separation of two amino acids, phenylalanine and tryptophan, using an ion exchange resin. The operating parameters for the one-column process and four-zone SMB were obtained from equilibrium theory.
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