The study for the mouse cerebellum developments irradiated with γ-ray during embryogenesis
2005
Park, I.K. (Chungnam National University, Daejeon, Republic of Korea) | Lee, G.J. (Chung Nam Veterinary Service Laboratory, Daejeon, Republic of Korea) | Lee, K.Y. (Daejeon University, Daejeon, Republic of Korea) | Min, T.S. (Korea Science and Engineering Foundation, Daejeon, Republic of Korea) | Byun, M.W. (Korea Atomic Energy Research Institute, Daejeon, Republic of Korea) | Lee, K.Y. (Chungnam National University, Daejeon, Republic of Korea) | Park, O.S. (Chungnam National University, Daejeon, Republic of Korea) | Kim, S.H. (Chungnam National University, Daejeon, Republic of Korea) | Yook, H.S. (Chungnam National University, Daejeon, Republic of Korea) | Kim, M.K. (Chungnam National University, Daejeon, Republic of Korea), E-mail: mgkim@cnu.ac.kr
In order to study about the lobule and layer formation and cell migration of the mouse cerebellum from at the birth to 15th day effected by 2.5, 5 and 10 Gy r-raddiation at the 19th pregnancy. The routine tissue preparation and staining procedure, Immunohistochemical staining method by the several antibody and western brotting method were utilized from the birth to the 15th day. The results were as followings. 1. The body and cerebellum weights were more slowly increase of the the 2.5 Gy, 5 Gy and 10 Gy irradiation group compare to the control group, and the health condition of the 2.5 Gy group was a little bad. but the 10 Gy group was more severe and begun to die from the 12th day after birth.
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