Soy [Glycine max] isoflavone aglycone modulates expression of cell surface antigens in vitro and in vivo
2007
Harada, T.(Tokyo Univ. of Pharmacy and Life Science, Hachioji (Japan)) | Arii, M. | Tsuji, R.F. | Adachi, Y. | Nakajima, M. | Yadomae, T. | Ohno, N.
Soy isoflavone aglycones (IFAs) have a wide range of biological actions. We investigated in this study the effect of IFAs on myeloid cells. The cell surface expression of both CD80 and CD86 was up-regulated by treating myeloid cells with IFAS in vitro and in vivo. The findings suggest that IFAs could modulate the myeloid cell function.
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