Toxicity of lectin extracted from Korean mistletoe (Viscum album coloratum) in piglets and its effects on the immunogenicity of Aujeszky's disease virus vaccines
2006
Yeo, S.G. (Kyungpook National University, Daegu, Republic of Korea), E-mail: sgyeo@knu.ac.kr
In the present study toxicity and immunostimulating activity of the lectin (KML-C), which was extracted from Korean mistletoe (Viscum album coloratum) were investigated in swine. To determine the toxicity, lectin was injected into thigh or cervical muscles of 4-week-old piglets (Landrace) and observed clinically and pathologically. For determinatio of the immunostimulating activity, lectin (0.7 ㎍/kg of body weight)-adjuvanted vaccine of Aujeszky's disease virus (ADV) (NYJ1-87) which was inactivated by 0.2% formalin was injected into the cervical muscle of antibody-negative piglets in the same age group.
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