Effects of Propyl Pyrazole Triol on the Blood Vessel-Dilation and Cellular Morphology of Liver and Kidney in Adult Male Mouse
2006
Lee, E.J. (Sunchon National University, Sunchon, Republic of Korea) | Lee, Y.M. (Sunchon National University, Sunchon, Republic of Korea) | Choe, E.S. (Pusan National University, Busan, Republic of Korea) | Seong, C.N. (Sunchon National University, Sunchon, Republic of Korea) | Cho, H.W. (Sunchon National University, Sunchon, Republic of Korea), E-mail: [email protected]
The present study was designed to characterize the effects of estrogen receptor agonist (4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol, PPT) on liver and kidney in male mouse using a light microscopic analysis. PPT was subcutaneously given to adult male mice at a weekly dosage of 178.6 mg/kg in a volume 0.08 ml of vehicle for 3, 5 and 8 weeks. There were differences in body and organ weights between control and the treated groups. Body and kidney weights were decreased in treated group whereas, liver weight was increased.
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