Comparison of osteoinductive efficacy of freezing, freeze-drying and defat-freezing implant preparation for allograft in rabbit
2007
Lee, J.I. (The University of Tokyo, Tokyo, Japan) | Song, H.N. (Seosin Animal Hospital, Jeonju, Republic of Korea) | Kim, N.S. (Chonbuk National University, Jeonju, Republic of Korea), E-mail: namsoo@chonbuk.ac.kr | Choi, I.H. (Chonbuk National University, Jeonju, Republic of Korea)
Bone allograft had been increased the need because autogenous bone graft is associated with donor site morbidity and is restricted in quantity. The bone allograft implants have to prepare properly for increasing osteoinductive ability and decreasing immune responses before providing to graft. The purpose of this study was to investigate the efficacy on new bone formation in bone allografts by treatment of implants. Cortical bone allografts were transplanted to experimental defects on midshaft of diaphyseal fibulae in 15 rabbits, which were divided to 3 experimental groups according to the preparation methods-freezing, freeze-drying, defat-freezing.
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