Small Black Soybean (Glycine max Merr.) Inhibits Mast Cell-mediated Allergic Reaction and Inflammatory Cytokine Secretion
2007
Shin, T.Y. (Woosuk University, Wanju, Republic of Korea), E-mail: tyshin@woosuk.ac.kr | Shin, H.Y. (Woosuk University, Wanju, Republic of Korea) | Lim, J.P. (Woosuk University, Wanju, Republic of Korea) | Kim, D.K. (Woosuk University, Wanju, Republic of Korea) | Chae, B.S. (Woosuk University, Wanju, Republic of Korea) | Kwon, Y.E. (Woosuk University, Wanju, Republic of Korea) | Oh, C.H. (Woosuk University, Wanju, Republic of Korea) | Cho, M.G. (Woosuk University, Wanju, Republic of Korea) | Lee, T.K. (Woosuk University, Wanju, Republic of Korea) | Park, J.S. (Nambu University, Gwangju, Republic of Korea) | Lee, J.H. (Nambu University, Gwangju, Republic of Korea) | Jeon, H. (Woosuk University, Wanju, Republic of Korea), E-mail: jeonh@woosuk.ac.kr
The mast cell-mediated immediate-type allergic reaction is involved in many allergic diseases such as asthma, allergic rhinitis, and sinusitis. The discovery of drugs for the treatment of mast cell-mediated immediate-type allergic diseases is a very important subject in human health. In this study, we investigated the effect of small black soybean (Glycine max Merr.) (Leguminosae) on mast cell-mediated allergic reaction and pro-inflammatory cytokine secretion. Small black soybean (SBS) inhibited compound 48/80-induced systemic reaction.
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